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1. (WO2014177464) INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/177464    International Application No.:    PCT/EP2014/058449
Publication Date: 06.11.2014 International Filing Date: 25.04.2014
IPC:
C07C 59/70 (2006.01), C07D 207/337 (2006.01), C07D 209/42 (2006.01), C07D 235/28 (2006.01), C07D 307/68 (2006.01), C07D 317/60 (2006.01), C07D 471/04 (2006.01), C07D 493/04 (2006.01), A61K 31/194 (2006.01), A61K 31/341 (2006.01), A61K 31/35 (2006.01), A61K 31/36 (2006.01), A61K 31/40 (2006.01), A61K 31/404 (2006.01), A61K 31/4184 (2006.01)
Applicants: HEINRICH-HEINE-UNIVERSITÄT DÜSSELDORF [DE/DE]; Universitätsstraße 1 40225 Düsseldorf (DE)
Inventors: METZ, Alexander; (DE).
GOHLKE, Holger; (DE).
SCHANDA, Julia; (DE).
WICHMANN, Christian; (DE).
GREZ, Manuel; (DE)
Agent: BÜLLE, Jan; Kutzenberger Wolff & Partner Theodor-Heuss-Ring 23 50668 Cologne (DE)
Priority Data:
13165993.0 30.04.2013 EP
Title (EN) INHIBITORS OF NHR2 AND/OR RUNX1/ETO-TETRAMERIZATION
(FR) INHIBITEURS DE LA TÉTRAMÉRISATION DE NHR2 ET/OU RUNX1/ETO
Abstract: front page image
(EN)The invention relates to inhibitors of the NHR2 tetramerization and their use as tumor therapeutics (e.g. against acute myeloid leukemia (AML)), cytostatics, and diagnostic agents.
(FR)L'invention concerne des inhibiteurs de la tétramérisation de NHR2 et leur utilisation en tant que produits thérapeutiques antitumoraux (par exemple, contre la leucémie myéloïde aiguë (AML)), des cytostatiques et des agents de diagnostic.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)