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1. WO2014174524 - A NOVEL COMPOSITION FOR NONALCOHOLIC FATTY LIVER DISEASE (NAFLD)

Publication Number WO/2014/174524
Publication Date 30.10.2014
International Application No. PCT/IN2013/000391
International Filing Date 25.06.2013
Chapter 2 Demand Filed 29.10.2014
IPC
A61K 31/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 31/40 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61P 1/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
CPC
A61K 31/40
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A61P 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Y10S 514/893
YSECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
10TECHNICAL SUBJECTS COVERED BY FORMER USPC
STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
514Drug, bio-affecting and body treating compositions
893Liver disorder
Applicants
  • CADILA HEALTHCARE LIMITED [IN]/[IN]
Inventors
  • PATEL, Pankaj
  • HARIPRASAD JANI, Rajendrakumar
Agents
  • GANDHI, Ritu
Priority Data
1468/MUM/201322.04.2013IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A NOVEL COMPOSITION FOR NONALCOHOLIC FATTY LIVER DISEASE (NAFLD)
(FR) NOUVELLE COMPOSITION POUR LA STÉATOSE HÉPATIQUE NON ALCOOLIQUE (NAFLD)
Abstract
(EN)
The present invention provides a compound of Formula (I) or pharmaceutical acceptable thereof, wherein 'R' is herein described. In addition, the invention relates to composition comprising effective therapeutic amount of compound of formula (I) and methods of using the compounds for treating or prevention disorder such as nonalcoholic fatty liver disease (NAFLD) including fatty liver (steatosis), nonalcoholic steatohepatitis (NASH), and cirrhosis (advanced scarring of the liver).
(FR)
La présente invention concerne un composé de formule (I) ou un produit pharmaceutique acceptable correspondant, où 'R' est décrit dans la description. De plus, l'invention concerne une composition comprenant une quantité thérapeutique efficace du composé de formule (I) et des procédés d'utilisation des composés pour traiter ou prévenir des troubles tels que la stéatose hépatique non alcoolique (NAFLD) comprenant le foie stéatosique (stéatose), la stéatohépatite non alcoolique (NASH) et la cirrhose (cicatrisation avancée du foie).
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