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1. WO2014169456 - USE OF 7-Α-[9-(4,4,5,5,5 - PENTAFLUORO-PENTYL-SULFINYL)NONYL]-ESTRA-1,3,5(10)-TRIENE-3,17Β-DIOL AND DERIVATIVES THEREOF

Publication Number WO/2014/169456
Publication Date 23.10.2014
International Application No. PCT/CN2013/074346
International Filing Date 18.04.2013
IPC
A61K 31/565 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
565not substituted in position 17 beta by a carbon atom, e.g. oestrane, oestradiol
A61P 5/30 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
5Drugs for disorders of the endocrine system
24of the sex hormones
30Oestrogens
A61P 19/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
CPC
A61K 31/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
095Sulfur, selenium, or tellurium compounds, e.g. thiols
10Sulfides; Sulfoxides; Sulfones
A61K 31/565
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives, e.g. steroids
565not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
A61K 9/0019
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
A61K 9/107
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
107Emulsions ; ; Emulsion preconcentrates; Micelles
A61P 19/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
A61P 29/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or anti-inflammatory agents, e.g antirheumatic agents; Non-steroidal anti-inflammatory drugs (NSAIDs)
Applicants
  • 西安力邦医药科技有限责任公司 XI'AN LIBANG PHARMACEUTICAL TECHNOLOGY CO., LTD. [CN]/[CN]
Inventors
  • 焦亚奇 JIAO, Yaqi
  • 王九成 WANG, Jiucheng
  • 胡忍乐 HU, Renle
Agents
  • 北京泛华伟业知识产权代理有限公司 PANAWELL & PARTNERS, LLC
Priority Data
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) USE OF 7-Α-[9-(4,4,5,5,5 - PENTAFLUORO-PENTYL-SULFINYL)NONYL]-ESTRA-1,3,5(10)-TRIENE-3,17Β-DIOL AND DERIVATIVES THEREOF
(FR) UTILISATION DE 7-A-[9-(4,4,5,5,5-PENTAFLUORO-PENTYL-SULFINYL)NONYL]-ESTRA-1,3,5(10)-TRIÈNE-3,17B-DIOL ET DE SES DÉRIVÉS
(ZH) 7-α-[9-(4,4,5,5,5-五氟戊基亚硫酰基)壬基]-雌甾-1,3,5(10)-三烯-3,17β-二醇及其衍生物的用途
Abstract
(EN)
Provided in the present invention are the use of the following compound of formula A in the preparation of drugs for the treatment of tumor necrosis factor-related diseases and a method for treating tumor necrosis factor-related diseases, the method comprises: administering to a subject in need thereof a therapeutically effective amount of the following compound of formula A.
(FR)
L'invention concerne l'utilisation du composé suivant de formule A dans la préparation de médicaments pour le traitement de maladies apparentées au facteur de nécrose tumorale et un procédé de traitement des maladies apparentées au facteur de nécrose tumorale, le procédé comprenant l'administration à un sujet en ayant besoin d'une quantité thérapeutiquement efficace du composé suivant de formule A.
(ZH)
本发明提供以下式 A化合物在制备用于治疗肿瘤坏死因子相关疾病的药物中的用途以及一种治疗与肿瘤坏死因子有关的疾病的方法,所述方法包括向有需要的受试者给予治疗有效量的如下式 A化合物。
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