Processing

Please wait...

Settings

Settings

Goto Application

1. WO2014162167 - METHOD FOR PRODUCING SYNTHETIC HYDROXYAPATITE NANOPLATES AND NANOPOWDER CONTAINING SYNTHETIC HYDROXYAPATITE NANOPLATE

Publication Number WO/2014/162167
Publication Date 09.10.2014
International Application No. PCT/IB2013/052575
International Filing Date 30.03.2013
IPC
C01B 25/32 2006.01
CCHEMISTRY; METALLURGY
01INORGANIC CHEMISTRY
BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF
25Phosphorus; Compounds thereof
16Oxyacids of phosphorus; Salts thereof
26Phosphates
32Phosphates of magnesium, calcium, strontium, or barium
A61L 27/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for prostheses or for coating prostheses
02Inorganic materials
12Phosphorus-containing materials, e.g. apatite
CPC
A61L 27/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
27Materials for ; grafts or; prostheses or for coating ; grafts or; prostheses
02Inorganic materials
12Phosphorus-containing materials, e.g. apatite
C01B 25/322
CCHEMISTRY; METALLURGY
01INORGANIC CHEMISTRY
BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; ; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
25Phosphorus; Compounds thereof
16Oxyacids of phosphorus; Salts thereof
26Phosphates
32Phosphates of magnesium, calcium, strontium, or barium
322Preparation by neutralisation of orthophosphoric acid
Applicants
  • INSTYTUT WYSOKICH CISNIEN POLSKIEJ AKADEMII NAUK [PL]/[PL]
Inventors
  • SMOLEŃ, Dariusz
  • KĘDZIERSKA, Aleksandra
  • PIETRZYKOWSKA, Elżbieta
  • CHUDOBA, Tadeusz
  • ŁOJKOWSKI, Witold
  • ŚWIĘSZKOWSKI, Wojciech
  • KURZYDŁOWSKI, Krzysztof
Agents
  • ADAMCZYK, Piotr
Priority Data
Publication Language English (EN)
Filing Language Polish (PL)
Designated States
Title
(EN) METHOD FOR PRODUCING SYNTHETIC HYDROXYAPATITE NANOPLATES AND NANOPOWDER CONTAINING SYNTHETIC HYDROXYAPATITE NANOPLATE
(FR) PROCÉDÉ DE PRODUCTION DE NANOPLAQUES D'HYDROXYAPATITE SYNTHÉTIQUE ET NANOPOUDRE CONTENANT UNE NANOPLAQUE D'HYDROXYAPATITE SYNTHÉTIQUE
Abstract
(EN)
The method according to the invention relates to hydroxyapatite with a hexagonal structure. It includes a step of the precursor preparation in a form of homogeneous mixture of the suspension of calcium hydroxide in water and phosphoric acid, and a step of forming of crystalline nanostructures in such precursor. During the step of crystalline nanostructures formation the prepared precursor is subjected to microwave radiation having a power density in the range from 1 to 10 watts per 1 cm3 of the precursor for a period of 10 to 900 seconds. The nanopowder featured in the invention has the average size of nanonoplates, determined by the longest chord of the outline as a result of the designation of the particle size distribution during the dark-field imagining in the transmission electron microscope and its fitting to the resulting Gaussian distribution graph, in the range of 3 to 30 nm.
(FR)
Le procédé selon l'invention concerne une hydroxyapatite ayant une structure hexagonale. Il comprend une étape de préparation d'un précurseur sous forme d'un mélange homogène de la suspension d'hydroxyde de calcium dans de l'eau et d'acide phosphorique, et une étape de formation de nanostructures cristallines dans ce précurseur. Pendant l'étape de formation des nanostructures cristallines, le précurseur préparé est soumis à un rayonnement micro-ondes ayant une densité de puissance comprise dans la plage de 1 à 10 watts par cm3 du précurseur pour une durée de 10 à 900 secondes. La nanopoudre selon l'invention a la taille moyenne des nanoplaques, déterminée par la corde la plus longue du contour en conséquence de la désignation de la distribution granulométrique pendant l'imagerie sur fond noir au microscope électronique par transmission, et son ajustement à la courbe de distribution gaussienne qui en résulte, comprise dans la plage de 3 à 30 nm.
Latest bibliographic data on file with the International Bureau