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1. WO2014159938 - SUBSTITUTED AMINOTHIAZOLES FOR THE TREATMENT OF TUBERCULOSIS

Publication Number WO/2014/159938
Publication Date 02.10.2014
International Application No. PCT/US2014/025488
International Filing Date 13.03.2014
IPC
A61K 31/44 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
44Non-condensed pyridines; Hydrogenated derivatives thereof
A61K 31/427 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
425Thiazoles
427not condensed and containing further heterocyclic rings
CPC
C07D 277/50
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
277Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
02not condensed with other rings
20having two or three double bonds between ring members or between ring members and non-ring members
32with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
38Nitrogen atoms
50Nitrogen atoms bound to hetero atoms
C07D 417/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
417Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
02containing two hetero rings
04directly linked by a ring-member-to-ring-member bond
C07D 417/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
417Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
C07D 417/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
417Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
14containing three or more hetero rings
Applicants
  • THE BROAD INSTITUTE, INC. [US]/[US]
  • MASSACHUSETTS GENERAL HOSPITAL [US]/[US]
  • BRIGHAM AND WOMEN'S HOSPITAL [US]/[US]
Inventors
  • HUNG, Deborah
  • SERRANO-WU, Michael
  • GRANT, Sarah
  • KAWATE, Tomohiko
Agents
  • SCOLNICK, Daniel
Priority Data
61/779,10113.03.2013US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SUBSTITUTED AMINOTHIAZOLES FOR THE TREATMENT OF TUBERCULOSIS
(FR) AMINOTHIAZOLES SUBSTITUÉS POUR LE TRAITEMENT DE LA TUBERCULOSE
Abstract
(EN)
Disclosed are substituted aminothiazoles, which can be used for, among other things, the treatment of tuberculosis, pharmaceutical compositions containing the same, and methods of using the same.
(FR)
L'invention concerne des aminothiazoles substitués, qui peuvent être utilisés pour, parmi d'autres choses, le traitement de la tuberculose, des compositions pharmaceutiques les contenant et des procédés d'utilisation de ceux-ci.
Also published as
Latest bibliographic data on file with the International Bureau