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1. WO2014135655 - COMPOSITIONS AND METHODS FOR TREATING MUSCLE-INVASIVE BLADDER CANCER

Publication Number WO/2014/135655
Publication Date 12.09.2014
International Application No. PCT/EP2014/054384
International Filing Date 06.03.2014
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
C12Q 1/6886
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
C12Q 2600/106
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
C12Q 2600/154
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
154Methylation markers
C12Q 2600/158
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
158Expression markers
Applicants
  • INSTITUT CURIE [FR]/[FR]
  • CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE [FR]/[FR]
Inventors
  • RADVANYI, François
  • REBOUISSOU, Sandra
  • KAMOUN, Aurélie
  • ALLORY, Yves
  • DE REYNIES, Aurélien
  • BERNARD-PIERROT, Isabelle
  • LEBRET, Thierry
Agents
  • PIERRU, Bénédicte
Priority Data
13305253.006.03.2013EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR TREATING MUSCLE-INVASIVE BLADDER CANCER
(FR) COMPOSITIONS ET MÉTHODES DE TRAITEMENT DU CANCER DE LA VESSIE INVASIF POUR LE MUSCLE
Abstract
(EN)
The present invention relates to a method to classify patients suffering from a muscle-invasive bladder cancer for therapeutic intervention, in particular for selecting a patient afflicted with a muscle-invasive bladder cancer for a treatment comprising an EGFR kinase inhibitor and/or capecitabine.
(FR)
La présente invention concerne un procédé pour classifier des patients souffrants du cancer de la vessie invasif pour le muscle pour une intervention thérapeutique, en particulier pour la sélection d'un patient atteint du cancer de la vessie invasif pour le muscle pour un traitement comprenant un inhibiteur de kinase EGFR et/ou de capécitabine.
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