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1. WO2014128723 - ANTICANCER COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF

Publication Number WO/2014/128723
Publication Date 28.08.2014
International Application No. PCT/IN2014/000103
International Filing Date 19.02.2014
IPC
C07D 307/94 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
307Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
94spiro-condensed with carbocyclic rings or ring systems, e.g. griseofulvins
A61K 31/341 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
34having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
341not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07C 45/27
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
27by oxidation
C07C 45/61
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
61by reactions not involving the formation of >C = O groups
C07C 45/67
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
61by reactions not involving the formation of >C = O groups
67by isomerisation; by change of size of the carbon skeleton
C07C 67/347
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
67Preparation of carboxylic acid esters
30by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
333by isomerisation; by change of size of the carbon skeleton
343by increase in the number of carbon atoms
347by addition to unsaturated carbon-to-carbon bonds
C07D 301/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
301Preparation of oxiranes
Applicants
  • COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH [IN]/[IN]
Inventors
  • REDDY, Dumbala Srinivasa
  • HANDORE, Kishor Laxman
Agents
  • LAKSHMIKUMARAN, Malathi
Priority Data
0466/DEL/201319.02.2013IN
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) ANTICANCER COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF
(FR) COMPOSÉS ANTICANCÉREUX ET PROCÉDÉ DE LEUR PRÉPARATION
Abstract
(EN) The invention disclosed herein relates to novel Peribysin E analogues of general formula-I. Further the invention provides simple, economical and short synthesis of Peribysin E and its analogues of Formula I, in good yield and purity leading to the identification of more potent cell adhesion inhibitors.
(FR) L'invention concerne de nouveaux analogues de Péribysine E de formule générale I; l'invention permet aussi une synthèse simple, économique et rapide de Péribysine E et de ses analogues de formule I, avec un bon rendement et une pureté permettant l'identification d'inhibiteurs plus puissants d'adhésion cellulaire.
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