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1. WO2014124141 - METFORMIN DERIVATIVES FOR TREATING DIABETES

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Publication Number WO/2014/124141
Publication Date 14.08.2014
International Application No. PCT/US2014/015111
International Filing Date 06.02.2014
IPC
A01N 37/52 2006.1
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
37Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
52containing groups, e.g. carboxylic acid amidines
A61K 31/155 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines, e.g. amantadine
155Amidines , e.g. guanidine , isourea , isothiourea
A61K 31/385 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
38having sulfur as a ring hetero atom
385having two or more sulfur atoms in the same ring
CPC
C07D 339/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
339Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
02Five-membered rings
04having the hetero atoms in position 1,2, e.g. lipoic acid
Applicants
  • MYLARI, Banavara, L. [US]/[US]
Inventors
  • MYLARI, Banavara, L.
Agents
  • KATZ, Robert, D.
Priority Data
14/174,45406.02.2014US
61/761,76807.02.2013US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METFORMIN DERIVATIVES FOR TREATING DIABETES
(FR) DÉRIVÉS DE METFORMINE POUR LE TRAITEMENT DU DIABÈTE
Abstract
(EN) The invention provides mutual ternary salts of metformin, lipoie acid and acidic amino acids such as aspartic acid and glutamic acid. The invention further provides treatment of prediabetes, diabetes, diabetic complications and/or other conditions in mammals in a method that comprises administering an effective amount of one or more of the foregoing compositions to a mammal In need of such treatment.
(FR) L'invention concerne des sels ternaires mutuels de metformine, d'acide lipoïque et d'acides aminés acides tels que l'acide aspartique et l'acide glutamique. L'invention concerne de plus le traitement du prédiabète, du diabète, des complications diabétiques et/ou d'autres conditions chez les mammifères selon une méthode consistant à administrer une quantité efficace d'une ou plusieurs des susdites compositions à un mammifère ayant besoin d'un tel traitement.
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