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1. WO2014120021 - A COMBINATION MEDICAMENT COMPRISING PHENYLEPHRINE AND PARACETAMOL

Publication Number WO/2014/120021
Publication Date 07.08.2014
International Application No. PCT/NZ2014/000001
International Filing Date 07.01.2014
IPC
A61K 31/137 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines, e.g. amantadine
135having aromatic rings, e.g. methadone
137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
A61K 31/135 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines, e.g. amantadine
135having aromatic rings, e.g. methadone
A61K 31/167 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
167having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61P 11/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
02Nasal agents, e.g. decongestants
A61P 11/12 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
12Mucolytics
CPC
A61K 31/137
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines
135having aromatic rings ; , e.g. ketamine, nortriptyline
137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine ; or methadone
A61K 31/167
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
167having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61P 11/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 11/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
02Nasal agents, e.g. decongestants
A61P 11/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
12Mucolytics
Applicants
  • AFT PHARMACEUTICALS LIMITED [NZ]/[NZ]
Inventors
  • ATKINSON, Hartley Campbell
Agents
  • PIETRAS, Anthony Josef
Priority Data
60665904.02.2013NZ
61013202.05.2013NZ
61391802.08.2013NZ
61802720.11.2013NZ
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) A COMBINATION MEDICAMENT COMPRISING PHENYLEPHRINE AND PARACETAMOL
(FR) COMBINAISON MÉDICAMENTEUSE COMPRENANT LA PHÉNYLÉPHRINE ET LE PARACÉTAMOL
Abstract
(EN) Use of phenylephrine hydrochloride (or a pharmaceutically acceptable alternative form of phenylephrine) and paracetamol in the production of a combination medicament for treating upper respiratory mucosal congestion, comprising combining such substances with excipients, characterised in that the medicament has the phenylephrine hydrochloride (or the pharmaceutically acceptable alternative form of phenylephrine) and paracetamol in proportions suitable for, and the medicament is for, providing an adult with: a) 4 mg - 7.5 mg phenylephrine hydrochloride (or an equivalent amount of a pharmaceutically acceptable alternative form of phenylephrine), in combination with 950 mg - 1,000 mg paracetamol; or b) 5 mg - 7.5 mg phenylephrine hydrochloride (or an equivalent amount of a pharmaceutically acceptable alternative form of phenylephrine), in combination with 600 mg - 700 mg paracetamol; or c) 6 mg - 8 mg phenylephrine hydrochloride (or an equivalent amount of a pharmaceutically acceptable alternative form of phenylephrine), in combination with 500 mg - 550 mg paracetamol.
(FR) L'invention concerne l'utilisation d'hydrochlorure de phényléphrine (ou une forme alternative pharmaceutiquement acceptable de phényléphrine) et de paracétamol dans la production d'une combinaison médicamenteuse destinée à traiter la congestion des muqueuses des voies respiratoires supérieures, le procédé consistant à combiner lesdites substances avec des excipients, et caractérisé en ce que le médicament comprend l'hydrochlorure de phényléphrine (ou la forme alternative pharmaceutiquement acceptable de phényléphrine) et le paracétamol dans des proportions appropriées pour l'administrer à un adulte, ledit médicament étant destiné à un adulte, qui sont : a) de 4 mg à 7,5 mg d'hydrochlorure de phényléphrine, (ou une quantité équivalente d'une forme alternative pharmaceutiquement acceptable de phényléphrine) en combinaison avec une quantité de 950 mg à 1000 mg de paracétamol ; ou b) de 5 mg à 7,5 mg d'hydrochlorure de phényléphrine (ou une quantité équivalente d'une forme alternative pharmaceutiquement acceptable de phényléphrine) en combinaison avec une quantité de 600 mg à 700 mg de paracétamol ; ou c) de 6 mg à 8 mg d'hydrochlorure de phényléphrine (ou une quantité équivalente d'une forme alternative pharmaceutiquement acceptable de phényléphrine) en combinaison avec une quantité de 500 mg à 550 mg de paracétamol.
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