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1. WO2014118553 - NESTED SUPRAMOLECULAR CAPSULES

Publication Number WO/2014/118553
Publication Date 07.08.2014
International Application No. PCT/GB2014/050259
International Filing Date 30.01.2014
IPC
C08J 3/075 2006.1
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H142
3Processes of treating or compounding macromolecular substances
02Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
03in aqueous media
075Macromolecular gels
A61K 47/48 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
48the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
C08G 83/00 2006.1
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
83Macromolecular compounds not provided for in groups C08G2/-C08G81/104
B01J 13/14 2006.1
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
13Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
02Making microcapsules or microballoons
06by phase separation
14Polymerisation, crosslinking
CPC
A61K 9/4808
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
4808characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
B01J 13/14
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
13Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
02Making microcapsules or microballoons
06by phase separation
14Polymerisation; cross-linking
B01J 13/16
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
13Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
02Making microcapsules or microballoons
06by phase separation
14Polymerisation; cross-linking
16Interfacial polymerisation
B01J 13/22
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
13Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
02Making microcapsules or microballoons
20After-treatment of capsule walls, e.g. hardening
22Coating
C08G 83/008
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
83Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
008Supramolecular polymers
C08J 3/075
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G
3Processes of treating or compounding macromolecular substances
02Making solutions, dispersions or lattices by other methods than by solution, emulsion or suspension polymerisation techniques
03in aqueous media
075Macromolecular gels
Applicants
  • CAMBRIDGE ENTERPRISE LIMITED [GB]/[GB]
Inventors
  • ZHANG, Jing
  • COULSTON, Roger
  • PARKER, Richard
  • ABELL, Christopher
  • SCHERMAN, Oren
  • YU, Ziyi
Agents
  • WILLS, Jonathan
Priority Data
1301648.030.01.2013GB
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) NESTED SUPRAMOLECULAR CAPSULES
(FR) CAPSULES SUPRAMOLÉCULAIRES EMBOÎTÉES
Abstract
(EN) Provided is a nested capsule having a first capsule held within a second capsule. Each of the first and second capsules has a shell that is a supramolecular cross-linked network, such as a cucurbituril supramolecular cross-linked network. Each capsule shell is obtained or is obtainable from the complexation of a composition comprising a host, such as cucurbituril, and one or more building blocks having suitable guest functionality for the host, thereby to form a supramolecular cross-linked network. The nested capsules are suitable for delivering and selectively releasing an encapsulant at a location.
(FR) Cette invention concerne une capsule à emboîtement comprenant une première capsule contenue à l'intérieur d'une seconde capsule. Chacune des première et seconde capsules comporte une coque qui est un réseau réticulé supramoléculaire, tel qu'un réseau réticulé supramoléculaire de cucurbiturile. Chaque coque de capsule est obtenue ou peut être obtenue par complexation d'une composition comprenant un hôte, tel que le cucurbiturile, et une ou plusieurs entités moléculaires dotées d'une fonctionnalité d'invité convenables, pour former ainsi un réseau réticulé supramoléculaire. Les capsules emboîtées conviennent pour l'administration et la libération sélective d'un agent d'encapsulation à un endroit.
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