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1. WO2014118258 - HYPERPOLARIZED ESTERS AS METABOLIC MARKERS IN MR

Publication Number WO/2014/118258
Publication Date 07.08.2014
International Application No. PCT/EP2014/051760
International Filing Date 30.01.2014
IPC
A61K 49/10 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
06Nuclear magnetic resonance (NMR) contrast preparations; Magnetic resonance imaging (MRI) contrast preparations
08characterised by the carrier
10Organic compounds
CPC
A61K 49/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
A61K 49/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
08characterised by the carrier
10Organic compounds
A61K 51/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
51Preparations containing radioactive substances for use in therapy or testing in vivo
02characterised by the carrier ; , i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
04Organic compounds
Applicants
  • BRACCO IMAGING SPA [IT]/[IT]
Inventors
  • JENSEN, Pernille Rose
  • LERCHE, Mathilde H.
  • KARLSSON, Magnus
  • CABELLA, Claudia
  • COLOMBO SERRA, Sonia
  • MIRAGOLI, Luigi
  • VENTURI, Luca
  • TEDOLDI, Fabio
Agents
  • RAVIZZA, Claudio
Priority Data
13153469.531.01.2013EP
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) HYPERPOLARIZED ESTERS AS METABOLIC MARKERS IN MR
(FR) ESTERS HYPERPOLARISÉS UTILISÉS EN TANT QUE MARQUEURS MÉTABOLIQUES EN RM
Abstract
(EN) The invention relates to a method of Magnetic Resonance (MR) detection, in particular 13C-MR detection, by using a diagnostic medium comprising a hyperpolarized ester, in particular ethyl acetoacetate. The method comprises the detection of the MR signal of a hyperpolarized 13C carboxylic ester and of its respective hyperpolarized metabolite.
(FR) La présente invention concerne une méthode de détection par résonance magnétique (RM), en particulier une détection par RM-13C, à l'aide d'un moyen de diagnostic comprenant un ester hyperpolarisé, en particulier de l'acétoacétate d'éthyle. La méthode fait appel à la détection du signal de RM d'un ester carboxylique 13C et de son métabolite hyperpolarisé respectif.
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KR1020217014828This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
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