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1. WO2014102265 - METHODS AND COMPOSITIONS RELATING TO CRM197

Publication Number WO/2014/102265
Publication Date 03.07.2014
International Application No. PCT/EP2013/077968
International Filing Date 24.12.2013
IPC
A61K 47/48 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
48the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
C07K 14/34 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
34from Corynebacterium (G)
C12N 15/73 2006.1
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
70Vectors or expression systems specially adapted for E. coli
73Expression systems using phage lambda regulatory sequences
CPC
C07K 14/34
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
34from Corynebacterium (G)
Applicants
  • GLYCOVAXYN AG [CH]/[CH]
  • EIDGENÖSSISCHE MATERIALPRÜFUNGS- UND FORSCHUNGSANSTALT [CH]/[CH]
Inventors
  • IHSSEN, Julian
  • KOWARIK, Michael
  • THÖNY-MEYER, Linda Christiane
Agents
  • BEZZUBOVA, Olga
Priority Data
61/746,36627.12.2012US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND COMPOSITIONS RELATING TO CRM197
(FR) PROCÉDÉS ET COMPOSITIONS SE RAPPORTANT À CRM197
Abstract
(EN) The present invention provides novel methods of producing diphtheria toxin. In particular, the present invention provides novel methods of producing nontoxic forms of diphtheria toxin, e.g., CRM197. The present invention also provides novel compositions comprising diphtheria toxin or nontoxic forms of diphtheria toxin, e.g., CRM197.
(FR) La présente invention concerne des procédés d'un nouveau type pour la production d'une toxine de la diphtérie. En particulier, la présente invention concerne des procédés d'un nouveau type pour la production de formes non toxiques de toxine de la diphtérie, par exemple, CRM197. La présente invention concerne également des compositions d'un nouveau type comprenant une toxine de la diphtérie ou des formes non toxiques de toxine de la diphtérie, par exemple, CRM197.
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BR112015015268This application is not viewable in PATENTSCOPE because the national phase entry has not been published yet or the national entry is issued from a country that does not share data with WIPO or there is a formatting issue or an unavailability of the application.
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