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1. WO2014101941 - METHOD FOR MANUFACTURING AN OIL-IN-WATER EMULSION FROM AN OILY ACTIVE SUBSTANCE, FOR COSMETIC, FOOD, OR PHARMACEUTICAL USE

Publication Number WO/2014/101941
Publication Date 03.07.2014
International Application No. PCT/EP2012/076948
International Filing Date 27.12.2012
IPC
A61K 8/06 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
04Dispersions; Emulsions
06Emulsions
A61Q 9/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
9Preparations for removing hair or for aiding hair removal
CPC
A23D 7/04
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
7Edible oil or fat compositions containing an aqueous phase, e.g. margarines
02characterised by the production or working-up
04Working-up
A23L 29/20
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
29Foods or foodstuffs containing additives
20containing gelling or thickening agents
A23V 2002/00
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
2002Food compositions, function of food ingredients or processes for food or foodstuffs
A61K 2800/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
10General cosmetic use
A61K 2800/21
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
20Chemical, physico-chemical or functional or structural properties of the composition as a whole
21Emulsions characterized by droplet sizes below 1 micron
A61K 2800/33
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
20Chemical, physico-chemical or functional or structural properties of the composition as a whole
30Characterized by the absence of a particular group of ingredients
33Free of surfactant
Applicants
  • AR2I [FR]/[FR]
  • EPIPHANI, Jean-Claude [FR]/[FR]
Inventors
  • EPIPHANI, Jean-Claude
Agents
  • ARGYMA
Priority Data
Publication Language French (fr)
Filing Language French (FR)
Designated States
Title
(EN) METHOD FOR MANUFACTURING AN OIL-IN-WATER EMULSION FROM AN OILY ACTIVE SUBSTANCE, FOR COSMETIC, FOOD, OR PHARMACEUTICAL USE
(FR) PROCEDE DE FABRICATION D'UNE EMULSION AQUEUSE D'UNE SUBSTANCE ACTIVE HUILEUSE POUR APPLICATION COSMETIQUE, ALIMENTAIRE OU PHARMACEUTIQUE
Abstract
(EN) The invention relates to a method which includes the following steps: mixing hydrophilic components, including water and an emulsifying saponin which is less than 1% of the emulsion regardless of the proportion of the oily phase; mixing lipophilic components, including the oily active substance, which can reach 40% of the emulsion; a first homogenization of the two preceding phases using a rotor/stator or ultrasonic mixer until a mean diameter of less than 6 μm of the oily droplets is obtained; and a second homogenization of the preceding mixture using a high-pressure homogenizer until a mean diameter of less than 0.4 μm of the oily droplets is obtained.
(FR) Le procédé comprend les étapes suivantes : mélange de composants hydrophiles, comprenant de l'eau, un saponoside émulsionnant, celui-ci représentant moins de 1 % de l'émulsion quel que soit la proportion de phase huileuse; mélange de composants lipophiles, comprenant la substance active huileuse, celle-ci pouvant atteindre 40 % de l'émulsion; homogénéisation n° 1 des deux phases précédentes à l'aide d'un mélangeur du type rotor-stator, ou à ultra-sons, jusqu'à l'obtention d'un diamètre moyen des gouttelettes huileuses inférieur à 6 μm; homogénéisation n° 2 du mélange précédent à l'aide d'un homogénéiseur à haute pression, jusqu'à l'obtention d'un diamètre moyen des gouttelettes huileuses inférieur à 0,4 μm.
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