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Machine translation
1. (WO2014100779) METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/100779    International Application No.:    PCT/US2013/077334
Publication Date: 26.06.2014 International Filing Date: 21.12.2013
IPC:
A61K 35/14 (2006.01), A61K 35/12 (2006.01), A61K 38/36 (2006.01)
Applicants: OCATA THERAPEUTICS, INC. [US/US]; 33 Locke Drive Marlborough, MA 01752 (US)
Inventors: FENG, Qiang; (US).
LU, Shi-jiang; (US).
LANZA, Robert, P.; (US)
Agent: TREVISAN, Maria, A.; Wolf, Greenfield & Sacks, P.C. 600 Atlantic Avenue Boston, MA 02210-2206 (US)
Priority Data:
61/740,699 21.12.2012 US
61/787,476 15.03.2013 US
Title (EN) METHODS FOR PRODUCTION OF PLATELETS FROM PLURIPOTENT STEM CELLS AND COMPOSITIONS THEREOF
(FR) PROCÉDÉS DE PRODUCTION DE PLAQUETTES À PARTIR DE CELLULES SOUCHES PLURIPOTENTES, ET COMPOSITIONS ASSOCIÉES
Abstract: front page image
(EN)Methods for production of platelets from pluripotent stem cells, such as human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) are provided. These methods may be performed without forming embryoid bodies or clusters of pluripotent stem cells, and may be performed without the use of stromal inducer cells. Additionally, the yield and/or purity can be greater than has been reported for prior methods of producing platelets from pluripotent stem cells. Also provided are compositions and pharmaceutical preparations comprising platelets, preferably produced from pluripotent stem cells.
(FR)L'invention concerne des procédés de production de plaquettes à partir de cellules souches pluripotentes, telles que des cellules souches embryonnaires humaines (hESC) et des cellules souches pluripotentes induites (iPSC). Ces procédés peuvent être réalisés sans former des corps embryonnaires ou des groupes de cellules souches pluripotentes, et peuvent être réalisés sans l'utilisation de cellules inductrices stromales. De plus, le rendement et/ou la pureté peuvent être supérieurs à ce qui a été rapporté pour des procédés antérieurs de production de plaquettes à partir de cellules souches pluripotentes. L'invention concerne également des compositions et des préparations pharmaceutiques comprenant des plaquettes, de préférence produites à partir de cellules souches pluripotentes.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)