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1. WO2014095700 - NOVEL COMPOUNDS

Publication Number WO/2014/095700
Publication Date 26.06.2014
International Application No. PCT/EP2013/076672
International Filing Date 16.12.2013
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
487
Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02
in which the condensed system contains two hetero rings
04
Ortho-condensed systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
495
having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505
Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
519
ortho- or peri-condensed with heterocyclic rings
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1
Drugs for disorders of the alimentary tract or the digestive system
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
C07D 487/04 (2006.01)
A61K 31/519 (2006.01)
A61P 1/00 (2006.01)
A61P 11/00 (2006.01)
CPC
A61K 9/0053
A61K 9/007
C07C 309/04
C07C 309/08
C07C 309/20
C07C 309/29
Applicants
  • CHIESI FARMACEUTICI S.P.A. [IT/IT]; Via Palermo, 26/A I-43100 Parma, IT
Inventors
  • ALCARAZ, Lilian; IT
  • HEALD, Robert Andrew; IT
  • SUTTON, Jonathan Mark; IT
  • ARMANI, Elisabetta; IT
  • CAPALDI, Carmelida; IT
Agents
  • MINOJA, Fabrizio; Bianchetti Bracco Minoja S.r.l. Via Plinio, 63 I-20129 Milano, IT
Priority Data
12197767.218.12.2012EP
13158757.812.03.2013EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NOVEL COMPOUNDS
(FR) NOUVEAUX COMPOSÉS
Abstract
(EN)
This invention relates to heterocyclic compounds, which are pyrimidinone derivatives having human neutrophil elastase inhibitory properties, and their use in therapy.
(FR)
L'invention concerne des composés hétérocycliques qui sont des dérivés de la pyrimidinone présentant des propriétés d'inhibition de l'élastase neutrophile humaine, et leur utilisation à titre thérapeutique.
Also published as
AEP703/2015
CL2015-1678
CO15137457
GE13860
GE13860/1
IDIDP00201503633
MA38195
MXMX/a/2015/007379
PH12015501043
RSP-2018/1517
UAa201505958
Latest bibliographic data on file with the International Bureau