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1. WO2014086927 - COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY

Publication Number WO/2014/086927
Publication Date 12.06.2014
International Application No. PCT/EP2013/075672
International Filing Date 05.12.2013
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
453
Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
02
containing not further condensed quinuclidine ring systems
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
439
the ring forming part of a bridged ring system, e.g. quinuclidine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04
Antibacterial agents
08
for leprosy
C07D 453/02 (2006.01)
A61K 31/439 (2006.01)
A61P 11/06 (2006.01)
A61P 31/08 (2006.01)
CPC
A61K 31/4709
A61K 31/496
A61K 45/06
A61K 9/0073
A61M 15/0045
A61M 15/009
Applicants
  • CHIESI FARMACEUTICI S.P.A. [IT/IT]; Via Palermo, 26/A I-43100 Parma, IT
Inventors
  • RANCATI, Fabio; IT
  • LINNEY, Ian; IT
  • KNIGHT, Chris; IT
  • SCHMIDT, Wolfgang; IT
Agents
  • MINOJA, Fabrizio; Bianchetti Bracco Minoja S.r.l. Via Plinio, 63 I-20129 Milano, IT
Priority Data
12195898.706.12.2012EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY
(FR) COMPOSÉS AYANT UNE ACTIVITÉ ANTAGONISTE DU RÉCEPTEUR MUSCARINIQUE ET AGONISTE DU RÉCEPTEUR BÊTA2 ADRÉNERGIQUE
Abstract
(EN)
The present invention relates to compounds acting both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists, to processes for their preparation, to compositions comprising them, to therapeutic uses and combinations with other pharmaceutical active ingredients.
(FR)
La présente invention concerne des composés agissant à la fois en tant qu'antagonistes du récepteur muscarinique et agonistes du récepteur bêta2 adrénergique, leurs procédés de préparation, des compositions les comprenant, des utilisations thérapeutiques et des combinaisons avec d'autres principes pharmaceutiquement actifs.
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