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1. WO2014062055 - SYSTEM AND METHOD FOR OPERATING PARALLEL REACTORS

Publication Number WO/2014/062055
Publication Date 24.04.2014
International Application No. PCT/NL2013/050723
International Filing Date 11.10.2013
Chapter 2 Demand Filed 04.08.2014
IPC
B01J 19/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
CPC
B01J 19/0006
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
0006Controlling or regulating processes
B01J 19/0046
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
B01J 19/0093
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
0093Microreactors, e.g. miniaturised or microfabricated reactors
B01J 2219/00286
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00277Apparatus
00279Features relating to reactor vessels
00281Individual reactor vessels
00286Reactor vessels with top and bottom openings
B01J 2219/00585
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
00583Features relative to the processes being carried out
00585Parallel processes
B01J 2219/00689
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
2219Chemical, physical or physico-chemical processes in general; Their relevant apparatus
00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
0068Means for controlling the apparatus of the process
00686Automatic
00689using computers
Applicants
  • AVANTIUM TECHNOLOGIES B.V. [NL]/[NL]
Inventors
  • MOONEN, Roelandus Hendrikus Wilhelmus
Agents
  • BLOKHUIS, S.E.D.
Priority Data
200965918.10.2012NL
61/715,54418.10.2012US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SYSTEM AND METHOD FOR OPERATING PARALLEL REACTORS
(FR) SYSTÈME ET PROCÉDÉ POUR FAIRE FONCTIONNER DES RÉACTEURS PARALLÈLES
Abstract
(EN)
The invention pertains to a system for operating parallel reactors, which comprises: -a plurality of reactor assemblies, each reactor assembly comprising: -a flow-through reactor -a reactor feed line, -a reactor effluent line, -a primary fluid source, -a flow splitter which is arranged downstream of the primary fluid source and upstream of the reactor assemblies, and wherein all passive flow restrictors have an substantially equal resistance to fluid flow wherein the system further comprises a feed line pressure measurement device, wherein in each effluent line an individually controllable backpressure regulator is provided, and wherein further a pressure control arrangement is provided, said pressure control arrangement being linked to said feed line pressure measurement device and said backpressure regulators, said pressure control arrangement comprising an input device allowing to input a feed line pressure setpoint, said desired feed line pressure being the same for all reactor assemblies, wherein said pressure control arrangement is adapted to individually control the backpressure regulators such that the measured feed line pressure becomes substantially the same as the feed line pressure setpoint, and therewith substantially the same as the feed line pressures in the other reactor assemblies.
(FR)
La présente invention porte sur un système permettant de faire fonctionner des réacteurs parallèles, et qui comprend : -une pluralité d'ensembles réacteurs, chaque ensemble réacteur comprenant : -un réacteur à flux continu, -une ligne d'alimentation de réacteur, -une ligne d'effluent de réacteur, -une source de fluide principale, -un diviseur de flux qui est agencé en aval de la source de fluide principal et en amont des ensembles réacteurs, l'ensemble des limiteurs de débit passifs présentant une résistance sensiblement égale à l'écoulement de fluide, le système comprenant en outre un dispositif de mesure de pression de ligne d'alimentation, chaque ligne d'effluent disposant d'un régulateur de contre-pression pouvant être commandé individuellement, et comprenant en outre un système de régulation de pression, ledit système de régulation de pression étant relié audit dispositif de mesure de pression de ligne d'alimentation et auxdits régulateurs de contre-pression, ledit système de régulation de pression comprenant un dispositif d'entrée permettant d'entrer un point de consigne de pression de ligne d'alimentation, ladite pression de ligne d'alimentation souhaitée étant la même pour l'ensemble des ensembles réacteurs, ledit système de régulation de pression étant conçu pour commander individuellement les régulateurs de contre-pression de sorte que la pression de ligne d'alimentation devienne sensiblement identique au point de consigne de pression de ligne d'alimentation et, de ce fait, sensiblement identique aux pressions de ligne d'alimentation dans les autres ensembles réacteurs.
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