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1. WO2014052989 - METHODS, SYSTEMS, AND ARRAYS FOR BIOMOLECULAR ANALYSIS

Publication Number WO/2014/052989
Publication Date 03.04.2014
International Application No. PCT/US2013/062773
International Filing Date 30.09.2013
Chapter 2 Demand Filed 28.08.2014
IPC
G01N 33/543 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
CPC
C40B 40/06
CCHEMISTRY; METALLURGY
40COMBINATORIAL TECHNOLOGY
BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
40Libraries per se, e.g. arrays, mixtures
04Libraries containing only organic compounds
06Libraries containing nucleotides or polynucleotides, or derivatives thereof
C40B 40/10
CCHEMISTRY; METALLURGY
40COMBINATORIAL TECHNOLOGY
BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
40Libraries per se, e.g. arrays, mixtures
04Libraries containing only organic compounds
10Libraries containing peptides or polypeptides, or derivatives thereof
G01N 2035/00158
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
35Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
00029provided with flat sample substrates, e.g. slides
00099Characterised by type of test elements
00158Elements containing microarrays, i.e. "biochip"
G01N 2035/00168
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
35Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
00029provided with flat sample substrates, e.g. slides
00168Manufacturing or preparing test elements
G01N 33/54366
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
54366Apparatus specially adapted for solid-phase testing
G01N 33/54386
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
543with an insoluble carrier for immobilising immunochemicals
54366Apparatus specially adapted for solid-phase testing
54386Analytical elements
Applicants
  • VIBRANT HOLDINGS, LLC [US]/[US]
Inventors
  • RAJASEKARAN, John J.
  • JAYARAMAN, Vasanth
  • WANG, Tianhao
  • BEI, Kang
  • KRISHNAMURTHY, Hari Krishnan
Agents
  • KRAMMER, André T.
Priority Data
61/707,75828.09.2012US
61/732,22130.11.2012US
61/765,58415.02.2013US
61/805,88427.03.2013US
61/866,51215.08.2013US
PCT/US2013/002519007.02.2013US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS, SYSTEMS, AND ARRAYS FOR BIOMOLECULAR ANALYSIS
(FR) PROCÉDÉS, SYSTÈMES ET ARRANGEMENTS D'ANALYSE BIOMOLÉCULAIRE
Abstract
(EN)
Disclosed herein are formulations, substrates, and arrays. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays. Also disclosed are methods for identifying peptide sequences useful for diagnosis and treatment of disorders, and methods for using the peptide sequences for diagnosis and treatment of disorders, e.g., celiac disorder. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules.
(FR)
La présente invention divulgue des formulations, des substrats et des arrangements. L'invention divulgue également des procédés de fabrication et d'utilisation des formulations, des substrats et des arrangements. L'invention divulgue également des procédés pour identifier des séquences peptidiques utilisables pour le diagnostic et le traitement de troubles et des procédés pour utiliser les séquences peptidiques pour le diagnostic et le traitement de troubles, par exemple la maladie cœliaque. Dans certains modes de réalisation, les substrats et les arrangements comprennent une couche poreuse pour la synthèse et la fixation de polymères ou de biomolécules.
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