WO2014020344 COMPOUNDS AND THEIR EFFECTS ON APPETITE CONTROL AND INSULIN SENSITIVITY

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Publication Number WO/2014/020344

Publication Date 06.02.2014

International Application No. PCT/GB2013/052056

International Filing Date 31.07.2013

IPC

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Applicants

IMPERIAL INNOVATIONS LIMITED [GB]/[GB]
THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW [GB]/[GB]

Inventors

FROST, Gary
MORRISON, Douglas
PRESTON, Thomas

Agents

THOMPSON, Toby Alexander

Priority Data

1213629.7

31.07.2012

Publication Language English (en)

Filing Language English (EN)

Designated States

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Title

(EN) COMPOUNDS AND THEIR EFFECTS ON APPETITE CONTROL AND INSULIN SENSITIVITY

(FR) COMPOSÉS ET LEURS EFFETS SUR LA RÉGULATION DE L'APPÉTIT ET LA SENSIBILITÉ À L'INSULINE

Abstract

(EN) The invention provides a propionate inulin ester for the reduction of appetite, food intake and/or calorie intake and/or to improve insulin sensitivity in a subject, and for the treatment or prevention of obesity or diabetes. The invention also provides compositions comprising a propionate inulin ester, methods using propionate inulin esters, functional food containing propionate inulin ester and methods of making propionate inulin esters.

(FR) La présente invention concerne un ester propionate d'inuline pour la réduction de l'appétit, de l'apport alimentaire et/ou de l'apport calorique et/ou pour améliorer la sensibilité à l'insuline chez un sujet, et pour le traitement ou la prévention de l'obésité ou du diabète. La présente invention concerne en outre des compositions comprenant un ester propionate d'inuline, des procédés d'utilisation d'esters propionate d'inuline, des aliments fonctionnels contenant l'ester propionate d'inuline et des procédés de préparation d'esters propionate d'inuline.

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45	Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06	Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8	Cosmetics or similar toilet preparations
18	characterised by the composition
72	containing organic macromolecular compounds
73	Polysaccharides

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31	Medicinal preparations containing organic active ingredients
70	Carbohydrates; Sugars; Derivatives thereof
715	Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
733	Fructosans, e.g. inulin

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
5	Drugs for disorders of the endocrine system
48	of the pancreatic hormones
50	for increasing or potentiating the activity of insulin

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
P	SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
3	Drugs for disorders of the metabolism
04	Anorexiants; Antiobesity agents

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1. WO2014020344 - COMPOUNDS AND THEIR EFFECTS ON APPETITE CONTROL AND INSULIN SENSITIVITY

C	CHEMISTRY; METALLURGY
08	ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
B	POLYSACCHARIDES; DERIVATIVES THEREOF
37	Preparation of polysaccharides not provided for in groups C08B1/-C08B35/110; Derivatives thereof

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1	Foods or foodstuffs; Their preparation or treatment
29	Modifying nutritive qualities of foods; Dietetic products
30	containing additives

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
L	FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
33	Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10	using additives

A	HUMAN NECESSITIES
23	FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
V	INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
2002	Food compositions, function of food ingredients or processes for food or foodstuffs

C	CHEMISTRY; METALLURGY
08	ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
L	COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
5	Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49	Preparations for testing in vivo
06	Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
08	characterised by the carrier
10	Organic compounds
12	Macromolecular compounds
126	Linear polymers, e.g. dextran, inulin, PEG

A	HUMAN NECESSITIES
61	MEDICAL OR VETERINARY SCIENCE; HYGIENE
K	PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49	Preparations for testing in vivo
06	Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
08	characterised by the carrier
10	Organic compounds
12	Macromolecular compounds
126	Linear polymers, e.g. dextran, inulin, PEG