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1. (WO2014018080) HIGHLY MULTIPLEX PCR METHODS AND COMPOSITIONS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2014/018080 International Application No.: PCT/US2012/066339
Publication Date: 30.01.2014 International Filing Date: 21.11.2012
IPC:
C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
NATERA, INC. [US/US]; 201 Industrial Street Suite 410 San Carlos, California 94070, US
Inventors:
ZIMMERMANN, Bernhard; US
HILL, Matthew M.; US
LACROUTE, Philippe Gilbert; US
DODD, Michael; US
Agent:
HEALY, Vicki, L.; Natera, Inc. 201 Industrial Road, Suite 410 San Carlos, CA 94070, US
Priority Data:
13/683,60421.11.2012US
61/675,02024.07.2012US
Title (EN) HIGHLY MULTIPLEX PCR METHODS AND COMPOSITIONS
(FR) PROCÉDÉS DE PCR HAUTEMENT MULTIPLEX ET COMPOSITIONS
Abstract:
(EN) The invention provides methods for simultaneously amplifying multiple nucleic acid regions of interest in one reaction volume as well as methods for selecting a library of primers for use in such amplification methods. The invention also provides library of primers with desirable characteristics, such as minimal formation of amplified primer dimers or other non-target amplicons.
(FR) L'invention concerne des procédés pour amplifier simultanément de multiples régions d'acide nucléique d'intérêt dans un volume de réaction ainsi que des procédés pour sélectionner une bibliothèque d'amorces utilisées dans des procédés d'amplification. L'invention concerne également une bibliothèque d'amorces avec des caractéristiques souhaitées, telle que la formation minimale de dimères d'amorce amplifiés ou d'autres amplicons non cibles.
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
CA2877493IL236435EP2847347SG11201408813VCN104685064JP2015526073
RU2014152883NZ703372AU2012385961ES2625079IN18/DELNP/2015RU0002650790
KR1020150038216