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1. (WO2014004677) METHOD OF REDUCING THE RISK OF PREGNANCY COMPLICATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2014/004677    International Application No.:    PCT/US2013/047896
Publication Date: 03.01.2014 International Filing Date: 26.06.2013
IPC:
A61K 35/56 (2006.01)
Applicants: MEMORIAL SLOAN-KETTERING CANCER CENTER [US/US]; 1275 York Avenue New York, New York 10065 (US)
Inventors: RUDENSKY, Alexander Y.; (US).
SAMSTEIN, Robert; (US).
JOSEFOWICZ, Steven; (US)
Agent: JARRELL, Brenda Herschbach; Choate, Hall & Stewart LLP Two International Place Boston, Massachusetts 02110 (US)
Priority Data:
61/664,898 27.06.2012 US
Title (EN) METHOD OF REDUCING THE RISK OF PREGNANCY COMPLICATIONS
(FR) PROCÉDÉ DE RÉDUCTION DU RISQUE DE COMPLICATIONS DE LA GESTATION
Abstract: front page image
(EN)The present invention relates to compositions and methods for reducing the risk of pregnancy complications, including miscarriage and preeclampsia. In particular, the invention provides compositions and methods for use in pregnancy complication risk assessment and prevention based on the use of pTregs. The present invention permits identification and/or characterization of pTreg levels, and also provides systems for using such pTreg levels, for example to assess and/or reduce risk of pregnancy complications.
(FR)La présente invention concerne des compositions et des procédés de réduction du risque de complications de la gestation, incluant l'avortement spontané et la pré-éclampsie. En particulier, l'invention concerne des compositions et des procédés à utiliser pour l'évaluation et la prévention du risque de complications de la gestation, basés sur l'utilisation des pTregs. La présente invention permet d'identifier et/ou de caractériser des niveaux de pTregs, et également d'obtenir des systèmes permettant d'utiliser de tels niveaux de pTregs, par exemple pour évaluer et/ou réduire le risque de complications de gestation.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)