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1. (WO2013186359) ANALYSIS METHOD ON THE BASIS OF AN ARRAY
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/186359 International Application No.: PCT/EP2013/062373
Publication Date: 19.12.2013 International Filing Date: 14.06.2013
IPC:
B01J 19/00 (2006.01) ,C12Q 1/68 (2006.01) ,G01N 33/543 (2006.01) ,C40B 60/14 (2006.01)
B PERFORMING OPERATIONS; TRANSPORTING
01
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
J
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS, COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19
Chemical, physical, or physico-chemical processes in general; Their relevant apparatus
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
543
with an insoluble carrier for immobilising immunochemicals
C CHEMISTRY; METALLURGY
40
COMBINATORIAL TECHNOLOGY
B
COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
60
Apparatus specially adapted for use in combinatorial chemistry or with libraries
14
for creating libraries
Applicants:
ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG [DE/DE]; Fahnenbergplatz 79085 Freiburg, DE
Inventors:
ROTH, Günter; DE
Agent:
LANGE, Sven; HERTIN Anwaltssozietät Kurfürstendamm 54-55 10707 Berlin, DE
Priority Data:
10 2012 105 165.814.06.2012DE
13154826.511.02.2013EP
Title (EN) ANALYSIS METHOD ON THE BASIS OF AN ARRAY
(FR) PROCÉDÉ D'ANALYSE À BASE D'UN RÉSEAU
(DE) ANALYSEVERFAHREN AUF BASIS EINES ARRAYS
Abstract:
(EN) The invention relates to a method for analyzing molecular properties and/or reaction conditions, comprising a step of providing a first store having a first surface, wherein a specific selection of sample molecules is directly or indirectly bonded to the surface in a defined arrangement, a step of producing at least two transfer stores, wherein at least two additional surfaces are provided, and a reaction step, selected from the group comprising a transfer reaction, an amplification reaction, and/or a derivatization reaction, whereby product molecules can arise and said product molecules and/or the sample molecules bond to the surfaces, wherein there is a clear spatial association between the sample molecules of the first store and the product molecules and/or sample molecules of the transfer stores and the first store, the transfer stores, the sample molecules, the product molecules, the transfer reaction, the amplification reaction, and/or the derivatization reaction is analyzed.
(FR) L'invention concerne un procédé d'analyse de propriétés moléculaires et/ou de conditions de réaction, comprenant la mise en œuvre d'un premier dispositif de stockage comprenant une première surface, l'établissement d'une liaison directe ou indirecte entre une sélection précise de molécules et ladite surface selon une disposition définie, la préparation d'au moins deux dispositifs de stockage de transfert en mettant en œuvre au moins deux autres surfaces, une étape de réaction qui est choisie dans le groupe d'une réaction de transfert, d'une réaction d'amplification et/ou d'une réaction de dérivatisation et qui permet d'obtenir des molécules de produit, lesdites molécules de produit et/ou les molécules à analyser entrant en liaison avec lesdites surfaces. Les molécules à analyser occupant le premier dispositif de stockage et les molécules de produit et/ou les molécules à analyser occupant les dispositifs de stockage de transfert peuvent être distinguées sans ambiguïté de par leur disposition dans l'espace, et ladite analyse concerne le premier dispositif de stockage, les dispositifs de stockage de transfert, les molécules à analyser, les molécules de produit, la réaction de transfert, la réaction d'amplification et/ou la réaction de dérivatisation.
(DE) Die Erfindung betrifft ein Verfahren zur Analyse von molekularen Eigenschaften und/oder Reaktionsbedingungen, umfassend die Bereitstellung eines ersten Speichers, umfassend eine erste Oberfläche, wobei eine gezielte Auswahl von Probemolekülen an die Oberfläche in einer definierten Anordnung direkt oder indirekt gebunden wird, die Herstellung von mindestens zwei Transferspeicher, wobei mindestens zwei weitere Oberflächen bereitgestellt werden, einen Reaktionsschritt, ausgewählt aus der Gruppe Übertragungsreaktion, Amplifikationsreaktion und/oder Derivatisierungsreaktion, wodurch Produktmoleküle entstehen können und diese Produktmoleküle und/oder die Probemoleküle an die Oberflächen binden, wobei eine ein-eindeutige räumliche Zuordnung zwischen den Probemolekülen des ersten Speichers und den Produktmolekülen und/oder Probemolekülen der Transferspeicher besteht und die Analyse des ersten Speichers, der Transferspeicher, der Probemoleküle, der Produktmoleküle, der Übertragungsreaktion, Amplifikationsreaktion und/oder Derivatisierungsreaktion erfolgt.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)