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1. (WO2013163453) CRYSTALLINE MICROSPHERES AND THE PROCESS FOR MANUFACTURING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/163453 International Application No.: PCT/US2013/038257
Publication Date: 31.10.2013 International Filing Date: 25.04.2013
IPC:
A61K 9/14 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
Applicants: SPI PHARMA, INC.[US/US]; 503 Carr Road Suite 210 Wilmington, DE 19809, US
Inventors: PROPST, Cecil, W.; US
MEADOWS, Marc, W.; US
TODD, Michael, S.; US
Agent: UDAL, Robert, P.; Morgan, Lewis & Bockius LLP 1701 Market Street Philadelphia, PA 19103-2921, US
Priority Data:
61/638,07325.04.2012US
61/783,60314.03.2013US
Title (EN) CRYSTALLINE MICROSPHERES AND THE PROCESS FOR MANUFACTURING THE SAME
(FR) MICROSPHÈRES CRISTALLINES ET LEUR PROCÉDÉ DE FABRICATION
Abstract:
(EN) The present invention relates to microspheres and compositions comprising a plurality of microspheres, wherein the microspheres are perfectly spherical and have a moisture content less than 1%, and the method of manufacturing the same. The present invention is useful in the manufacture of sustained and modified release active pharmaceutical ingredient (API) microspheres, as a free flowing excipient for mini-tablets and in the manufacture of API dispersions.
(FR) La présente invention concerne des microsphères et des compositions comprenant une pluralité de microsphères ‑ lesdites microsphères étant parfaitement sphériques et possédant une teneur en humidité inférieure à 1 % ‑, ainsi que leur procédé de fabrication. La présente invention est utile dans la fabrication de microsphères d'ingrédient pharmaceutique actif (IPA) à libération modifiée et soutenue, en tant qu'excipient à écoulement libre pour des mini-comprimés, et dans la fabrication de dispersions dudit (IPA).
front page image
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)