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1. (WO2013163142) LIQUID PHARMACEUTICAL FORMULATION CONTAINING KETOROLAC AND TRAMADOL
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/163142 International Application No.: PCT/US2013/037737
Publication Date: 31.10.2013 International Filing Date: 23.04.2013
IPC:
A61K 31/407 (2006.01) ,A61K 31/135 (2006.01) ,A61K 31/40 (2006.01) ,A61K 31/405 (2006.01) ,A61K 9/08 (2006.01) ,A61P 25/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
407
condensed with heterocyclic ring systems, e.g. ketorolac, physostigmine
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
13
Amines, e.g. amantadine
135
having aromatic rings, e.g. methadone
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403
condensed with carbocyclic rings, e.g. carbazole
404
Indoles, e.g. pindolol
405
Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
08
Solutions
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25
Drugs for disorders of the nervous system
Applicants:
YUNG SHIN PHARM. IND. CO., LTD.; 1191 Sec. 1 Chung Shan Rd., Tachia Taichung, 437, TW
Inventors:
SUN, Wei-Zen; TW
LEE, Fangchen; TW
TSAI, Chiung Ju; TW
TSAI, Yu-Hui; TW
HUANG, Hsiao-Chun; TW
LU, Wen-Jen; TW
JANG, Shin Hong; TW
Agent:
KUNG, Viola T.; Perkins Coie LLP P.O. Box 1208 Seattle, Washington 98111-1208, US
Priority Data:
61/638,43125.04.2012US
Title (EN) LIQUID PHARMACEUTICAL FORMULATION CONTAINING KETOROLAC AND TRAMADOL
(FR) FORMULATION PHARMACEUTIQUE LIQUIDE CONTENANT DU KÉTOROLAC ET DU TRAMADOL
Abstract:
(EN) The prevent invention relates to a liquid pharmaceutical composition for treating a patient having moderate to severe pain. The liquid pharmaceutical composition comprises an effective amount of ketorolac or ketorolac tromethamine, and an effective amount of tramadol or its pharmaceutically acceptable salt. The liquid pharmaceutical composition is effective in reducing pain score from 8-9 to 5.3 or less.
(FR) La présente invention concerne une composition pharmaceutique liquide pour le traitement d'un patient ayant une douleur modérée à sévère. La composition pharmaceutique liquide comprend une quantité efficace de kétorolac ou de kétorolac trométhamine, et une quantité efficace de tramadol ou de son sel pharmaceutiquement acceptable. La composition pharmaceutique liquide est efficace pour réduire l'évaluation de la douleur de 8 - 9 à 5,3 voire moins.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)