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Machine translation
1. (WO2013162654) METHODS FOR DETECTING ALLOSTERIC MODULATORS OF PROTEINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/162654    International Application No.:    PCT/US2013/000117
Publication Date: 31.10.2013 International Filing Date: 25.04.2013
IPC:
G01N 33/68 (2006.01), G01N 33/58 (2006.01)
Applicants: BIODESY, INC. [US/US]; 384 Oyster Point Blvd. #8 South San Francisco, CA 94080 (US)
Inventors: SALAFSKY, Joshua, S.; (US)
Agent: SKUBATCH, Maya; Wilson Sonsini Goodrich & Rosati 650 Page Mill Road Palo Alto, CA 94306-1050 (US)
Priority Data:
61/638,131 25.04.2012 US
13/794,277 11.03.2013 US
PCT/US2012/063286 02.11.2012 US
61/638,026 25.04.2012 US
Title (EN) METHODS FOR DETECTING ALLOSTERIC MODULATORS OF PROTEINS
(FR) PROCÉDÉS DE DÉTECTION DE MODULATEURS ALLOSTÉRIQUES DE PROTÉINES
Abstract: front page image
(EN)The present invention discloses, inter alia, methods for labeling a target protein with an SHG-active probe for detection by second harmonic or sum-frequency generation in order to identify agents which bind to an allosteric site on the target protein thereby altering its structural conformation
(FR)La présente invention concerne notamment des procédés de marquage d'une protéine cible avec une sonde active GSH pour la détection par génération de seconde harmonique ou génération de fréquence-somme. L'objectif est d'identifier des agents qui se lient à un site allostérique de la protéine cible, ce qui permet de modifier sa conformation structurale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)