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1. (WO2013161928) OXAZOLOTRIAZOLE DERIVATIVE AND DRUG COMPOSITION CONTAINING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/161928    International Application No.:    PCT/JP2013/062181
Publication Date: 31.10.2013 International Filing Date: 25.04.2013
IPC:
C07D 498/04 (2006.01), A61K 31/424 (2006.01), A61K 31/427 (2006.01), A61K 31/428 (2006.01), A61K 31/433 (2006.01), A61K 31/4439 (2006.01), A61K 31/454 (2006.01), A61K 31/4709 (2006.01), A61K 31/496 (2006.01), A61K 31/5377 (2006.01), A61K 31/551 (2006.01), A61P 25/04 (2006.01), A61P 29/00 (2006.01), A61P 43/00 (2006.01)
Applicants: SHIONOGI & CO., LTD. [JP/JP]; 1-8, Doshomachi 3-chome, Chuo-ku, Osaka-shi, Osaka 5410045 (JP)
Inventors: HATTORI, Kazunari; (JP).
TAKAYA, Kenji; (JP).
KAWASE, Kazuho; (JP).
AOKI, Natsue; (JP).
ISHIDA, Yoshihito; (JP)
Agent: TAKAYAMA, Hirotsugu; Shionogi & Co., Ltd. Intellectual Property Department, 1-1, Futabacho 3-chome, Toyonaka-shi, Osaka 5610825 (JP)
Priority Data:
2012-100687 26.04.2012 JP
Title (EN) OXAZOLOTRIAZOLE DERIVATIVE AND DRUG COMPOSITION CONTAINING SAME
(FR) DÉRIVÉ OXAZOLOTRIAZOLE ET COMPOSITION MÉDICAMENTEUSE CONTENANT CELUI-CI
(JA) オキサゾロトリアゾール誘導体およびそれらを含有する医薬組成物
Abstract: front page image
(EN)Disclosed is the compound represented by formula (I) or a pharmaceutically acceptable salt thereof (in the formula: R1a is a hydrogen atom or the like; R7 is the group represented by -C(R3a)(R4a)-N(R5a)-Y­a-R6a or the like; R3a and R4a are both hydrogen atoms or join together to form an oxo or the like; R5a is a hydrogen atom or the like; -Ya- is a single bond or the like; R6a is a hydrogen atom or the like; R8 is the group represented by -C(R16)(R17)-N(R18)-X-R19 or the like; R16 and R17 are both hydrogen atoms or join together to form an oxo or the like; R18 is a hydrogen atom or the like; -X- is a single bond or the like; and R19 is a hydrogen atom or the like).
(FR)L'invention concerne un composé de formule (I) ou un sel pharmaceutiquement acceptable de celui-ci. Dans ladite formule, R1a est un atome d'hydrogène ou analogue; R7 est le groupe représenté par -C(R3a)(R4a)-N(R5a)-Y­ a-R6a ou analogue; R3a et R4a sont tous deux des atomes d'hydrogène ou forment ensemble un oxo ou analogue; R5a est un atome d'hydrogène ou analogue; -Ya- est une liaison simple ou analogue; R6a est un atome d'hydrogène ou analogue; R8 est le groupe représenté par -C(R16)(R17)-N(R18)-X-R19 ou analogue; R16 et R17 sont tous deux des atomes d'hydrogène ou forment ensemble un oxo ou analogue; R18 est un atome d'hydrogène ou analogue; -X- représente une liaison simple ou analogue; et R19 est un atome d'hydrogène ou analogue).
(JA) 式(I):(式中、R1aは、水素原子等;Rは、-C(R3a)(R4a)-N(R5a)-Y-R6aで示される基等;R3aおよびR4aは、共に水素原子または一緒になってオキソ等;R5aは、水素原子等;-Y-は、単結合等;R6aは、水素原子等;Rは、-C(R16)(R17)-N(R18)-X-R19で示される基等;R16およびR17は、共に水素原子または一緒になってオキソ等;R18は、水素原子等;-X-は、単結合等;R19は、水素原子等;)で示される化合物またはその製薬上許容される塩。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)