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1. (WO2013161919) Trk-INHIBITING COMPOUND

Pub. No.:    WO/2013/161919    International Application No.:    PCT/JP2013/062158
Publication Date: Fri Nov 01 00:59:59 CET 2013 International Filing Date: Fri Apr 26 01:59:59 CEST 2013
IPC: C07D 417/14
A61K 31/444
A61K 31/506
A61K 31/55
A61P 1/04
A61P 11/02
A61P 11/06
A61P 13/02
A61P 17/04
A61P 25/04
A61P 37/08
A61P 43/00
Applicants: ONO PHARMACEUTICAL CO., LTD.
小野薬品工業株式会社
Inventors: TAKEUCHI, Jun
竹内 淳
IKURA, Masahiro
井倉 誠泰
HIGASHINO, Masato
東野 勝人
IWAHASHI, Maki
岩橋 摩紀
HASHIMURA, Kazuya
橋村 計哉
Title: Trk-INHIBITING COMPOUND
Abstract:
The purpose of the present invention is to provide is a drug the active ingredient of which is a compound that has Trk-inhibiting activity in the prevention and/or treatment of diseases such as pain, pruritus, lower urinary tract disorder, asthma, allergic rhinitis, inflammatory bowel disease and Chagas disease. A compound represented by general formula (I) (where each symbol has the same definition as the symbol described in the Specification), a salt thereof, an N-oxide thereof, or a solvate thereof, or a prodrug of the same, is useful as a drug ingredient having Trk-inhibiting activity in the prevention and/or treatment of disease such as pain, pruritus, lower urinary tract disorder, asthma, allergic rhinitis, inflammatory bowel disease and Chagas disease.