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1. (WO2013161814) ANTI-HUMAN CD69 ANTIBODY, AND USE THEREOF FOR MEDICAL PURPOSES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/161814    International Application No.:    PCT/JP2013/061918
Publication Date: 31.10.2013 International Filing Date: 23.04.2013
IPC:
C12N 15/09 (2006.01), A01K 67/027 (2006.01), A61K 39/395 (2006.01), A61P 29/00 (2006.01), A61P 37/08 (2006.01), C07K 16/28 (2006.01), C12N 1/15 (2006.01), C12N 1/19 (2006.01), C12N 1/21 (2006.01), C12N 5/10 (2006.01)
Applicants: GENEFRONTIER CORPORATION [JP/JP]; Todai-Kashiwa Venture Plaza Rm#308, 5-4-19, Kashiwa-no-Ha, Kashiwa-shi, Chiba 2770882 (JP).
NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY [JP/JP]; 1-33, Yayoi-cho, Inage-ku, Chiba-shi, Chiba 2638522 (JP)
Inventors: KOJOH, Kanehisa; (JP).
MIYAKOSHI, Akira; (JP).
KATOH, Shizue; (JP).
TSUIHIJI, Kumiko; (JP).
HAYAMI, Yuki; (JP).
NAKAMURA, Mikiko; (JP).
NAKAYAMA, Toshinori; (JP).
IWAMURA, Chiaki; (JP)
Agent: TAKASHIMA, Hajime; Meiji Yasuda Seimei Osaka Midosuji Bldg., 1-1, Fushimimachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410044 (JP)
Priority Data:
2012-098243 23.04.2012 JP
Title (EN) ANTI-HUMAN CD69 ANTIBODY, AND USE THEREOF FOR MEDICAL PURPOSES
(FR) ANTICORPS ANTI-CD69 HUMAIN, ET APPLICATION MÉDICALE DE CELUI-CI
(JA) 抗ヒトCD69抗体、及びその医薬用途
Abstract: front page image
(EN)The present invention provides an antibody which can bind to human CD69 specifically, has an activity of preventing allergic inflammations, and has a cross-reactivity with mouse CD69. The present invention also provides an antibody which has a high binding affinity for human CD69 and has an activity of preventing allergic inflammations. Each of the antibodies according to the present invention may be a human antibody.
(FR)L'invention fournit un anticorps qui se lie de manière spécifique à un CD69 humain, qui possède une activité inhibant les inflammations allergiques, et qui possède une activité croisée avec un CD69 de souris. En outre, l'invention fournit un anticorps qui possède une affinité de liaison élevée par rapport au CD69 humain, et qui possède une activité inhibant les inflammations allergiques. Ainsi, l'anticorps de l'invention peut être un anticorps humain.
(JA) 本発明は、ヒトCD69に特異的に結合し、アレルギー性炎症を抑制する活性を有する、抗体であって、マウスCD69に交差反応性を有する抗体を提供する。また、本発明はヒトCD69に対して高い結合親和性を有し、アレルギー性炎症を抑制する活性を有する抗体を提供する。本発明の抗体はヒト抗体であり得る。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)