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1. (WO2013160359) ANTI-PDGF-C ANTIBODIES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/160359 International Application No.: PCT/EP2013/058513
Publication Date: 31.10.2013 International Filing Date: 24.04.2013
IPC:
C07K 16/22 (2006.01) ,A61K 39/395 (2006.01) ,A61P 35/00 (2006.01) ,A61P 27/02 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
16
Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18
against material from animals or humans
22
against growth factors
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35
Antineoplastic agents
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
27
Drugs for disorders of the senses
02
Ophthalmic agents
Applicants: FROMOND, Claudia[FR/FR]; FR (US)
NGO, Hoa Thu[BE/BE]; BE (US)
ZWAAL, Richard[NL/BE]; BE (US)
NOTEBAERT, Sofie[BE/BE]; BE (US)
THROMBOGENICS N.V.[BE/BE]; Gaston Geenslaan 1 B-3001 Heverlee, BE (AllExceptUS)
Inventors: FROMOND, Claudia; FR
NGO, Hoa Thu; BE
ZWAAL, Richard; BE
NOTEBAERT, Sofie; BE
Priority Data:
12165314.124.04.2012EP
12192943.416.11.2012EP
61/637,37224.04.2012US
61/727,23116.11.2012US
Title (EN) ANTI-PDGF-C ANTIBODIES
(FR) ANTICORPS ANTI-PDGF-C
Abstract:
(EN) The invention relates to antibodies binding to the PDGF-C antigen and capable of inhibiting binding of PDGF-C to the PDGFRα receptor and of inhibiting PDGFRα activation by PDGF-C. Applications of such antibodies are also disclosed. These include treatment of cancer.
(FR) L'invention concerne des anticorps se liant à l'antigène PDGF-C et apte à inhiber la liaison de PDFG-C au récepteur PDGFRα et d'inhiber l'activation de PDGFRα par PDGF-C. L'invention concerne également des applications de ces anticorps. Celles-ci comprennent le traitement du cancer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)