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1. (WO2013160335) ANTIGENS AND ANTIGEN COMBINATIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/160335    International Application No.:    PCT/EP2013/058459
Publication Date: 31.10.2013 International Filing Date: 24.04.2013
IPC:
A61K 39/102 (2006.01), C07K 19/00 (2006.01), C07K 14/285 (2006.01), C12N 15/63 (2006.01), G01N 33/569 (2006.01), A61K 39/00 (2006.01), A61K 38/00 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35 CH-4056 Basel (CH)
Inventors: SORIANI, Marco; (IT).
SCARSELLI, Maria; (IT).
NORAIS, Nathalie; (IT).
GOMES MORIEL, Danilo; (IT).
ROSSI PACCANI, Silvia; (IT)
Agent: COURGEON, Antoine; Novartis Vaccines and Diagnostics SrL Via Fiorentina 1 I-53100 Siena (IT)
Priority Data:
1207385.4 26.04.2012 GB
12199079.0 21.12.2012 EP
Title (EN) ANTIGENS AND ANTIGEN COMBINATIONS
(FR) ANTIGÈNES ET COMBINAISONS D'ANTIGÈNES
Abstract: front page image
(EN)NTHI protein antigens have been identified and found to be conserved across several Haemophilus influenzae pathogenic strains. They have been isolated, cloned from a reference strain and tested for immunogenicity. Methods for immunization and vaccines derived thereof are also disclosed.
(FR)La présente invention concerne des antigènes de la protéine NTHI qui ont été identifiés et se sont avérés être conservés entre plusieurs souches pathogènes d'Haemophilus influenzae. Ils ont été isolés, clonés d'une souche de référence et leur immunogénicité a été testée. La présente invention concerne en outre des procédés d'immunisation et des vaccins dérivés de ceux-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)