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1. WO2013159055 - PRODUCTION OF FATTY ALCOHOLS FROM ENGINEERED MICROORGANISMS

Publication Number WO/2013/159055
Publication Date 24.10.2013
International Application No. PCT/US2013/037472
International Filing Date 19.04.2013
IPC
C12N 1/21 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
1Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
20Bacteria; Culture media therefor
21modified by introduction of foreign genetic material
C12P 7/06 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7Preparation of oxygen-containing organic compounds
02containing a hydroxy group
04acyclic
06Ethanol, i.e. non-beverage
C07C 31/125 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
31Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
02Monohydroxylic acyclic alcohols
125containing five to twenty-two carbon atoms
CPC
A61K 2800/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
10General cosmetic use
A61K 8/342
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
34Alcohols
342Alcohols having more than seven atoms in an unbroken chain
A61Q 19/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
C07C 31/125
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
CACYCLIC OR CARBOCYCLIC COMPOUNDS
31Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
02Monohydroxylic acyclic alcohols
125containing five to twenty-two carbon atoms
C11D 3/2031
CCHEMISTRY; METALLURGY
11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
DDETERGENT COMPOSITIONS
3Other compounding ingredients of detergent compositions covered in group C11D1/00
16Organic compounds
20containing oxygen
2003Alcohols; Phenols
2006Monohydric alcohols
2027unsaturated
2031fatty or with at least 8 carbon atoms in the alkenyl chain
C12N 15/70
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
70Vectors or expression systems specially adapted for E. coli
Applicants
  • CODEXIS, INC. [US]/[US]
Inventors
  • CHAN, Kaman
  • VALLE, Fernando
  • BARAK, Yoram
  • CLARK, Louis
  • KARLSHOEJ, Kristian
Agents
  • FLANAGAN, Lisa Dornbach
Priority Data
61/636,04420.04.2012US
61/674,05320.07.2012US
PCT/US2012/06944413.12.2012US
PCT/US2012/06955313.12.2012US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PRODUCTION OF FATTY ALCOHOLS FROM ENGINEERED MICROORGANISMS
(FR) PRODUCTION D'ALCOOLS GRAS PAR DES MICRO-ORGANISMES GÉNÉTIQUEMENT MODIFIÉS
Abstract
(EN)
The invention generally relates to the production of a fatty alcohol composition from recombinant microbial cells. The fatty alcohols are produced by expressing a gene encoding a heterologous fatty alcohol forming acyl-CoA reductase ("FAR"); a gene encoding a heterologous thioesterase ("TE") gene and a gene encoding an acyl-CoA synthetase ("ACS").
(FR)
Cette invention concerne d'une manière générale la production d'une composition d'alcools gras par des cellules microbiennes recombinées. Les alcools gras sont obtenus en exprimant un gène codant un alcool gras hétérologue formant une acyl-CoA réductase (FAR) ; un gène codant une thioestérase (TE) hétérologue et un gène codant une acyl-CoA synthétase (ACS).
Also published as
Latest bibliographic data on file with the International Bureau