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1. (WO2013158744) NANOPARTICLES OF CERIUM AND AMINO ACIDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/158744    International Application No.:    PCT/US2013/036943
Publication Date: 24.10.2013 International Filing Date: 17.04.2013
IPC:
B22F 9/24 (2006.01), A61K 9/14 (2006.01), A61K 9/51 (2006.01), C04B 35/632 (2006.01), A61K 47/00 (2006.01), A61K 48/00 (2006.01)
Applicants: CERION ENTERPRISES, LLC [US/US]; One Blossom Road Rochester, NY 14610 (US)
Inventors: COSTANZO, Wendi, Ann; (US).
REED, Kenneth, Joseph; (US).
STADLER, Bradford, Michael; (US)
Agent: O'SHAUGHNESSY, Brian, P.; RatnerPrestia P.O. Box 980 Valley Forge, PA 19482 (US)
Priority Data:
61/687,050 17.04.2012 US
Title (EN) NANOPARTICLES OF CERIUM AND AMINO ACIDS
(FR) NANOPARTICULES DE CÉRIUM ET ACIDES AMINÉS
Abstract: front page image
(EN)A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, an a-amino acid, an oxidant, and water is provided along with temperature conditions to effectively form nanoparticles. These biocompatible nanoparticles may be further conjugated to biologically active agents, such as plasmid DNA, siRNA or proteins, such that a cell transfection agent is formed.
(FR)La présente invention concerne un procédé de fabrication de nanoparticules de matériaux biocompatibles, un mélange de réaction aqueux comprenant l'ion céreux, un acide a-aminé, un oxydant, et de l'eau étant soumis à des conditions de température pour former efficacement des nanoparticules. Ces nanoparticules biocompatibles peuvent en outre être conjuguées à des agents biologiquement actifs, tels qu'un ADN plasmidique, un ARNsi ou des protéines, de sorte qu'un agent de transfection cellulaire soit formé.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)