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1. (WO2013158373) INDOLIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/158373    International Application No.:    PCT/US2013/035177
Publication Date: 24.10.2013 International Filing Date: 03.04.2013
IPC:
A61K 31/404 (2006.01)
Applicants: ANNJI PHARMACEUTICAL CO., LTD.; Rm 2, 12FL, No. 1, Guangfu S. Rd. Sungshan Chiu Taipei, Taiwan, R.O.C., 105 (TW).
HEALTHBANKS USA INC. [US/US]; 475 Wall Street Princeton, New Jersey 08540 (US) (ZA only)
Inventors: CHERN, Ji-Wang; (US).
JAGTAP, Ajit Dhananjay; (US).
WANG, Hsiao-Chun; (US).
CHEN, Grace Shiahuy; (US)
Agent: SAUNDERS, Hsiu-Ming; Ipc Intellectual Property Connections, Inc. 3346 Ramona Street Palo Alto, California 94306 (US)
Priority Data:
61/635,931 20.04.2012 US
Title (EN) INDOLIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS
(FR) DÉRIVÉS D'INDOLIN-2-ONE À TITRE D'INHIBITEURS DE PROTÉINES KINASES
Abstract: front page image
(EN)A novel class of indoline-2-one derivatives are disclosed. These compounds are protein kinase inhibitors which are useful for treating hyperproliferative diseases such as cancer. In one embodiment of the invention, the cancer is at least one selected from the group consisting of lung cancer, colorectal cancer, liver cancer and acute myelomonocytic leukemia.
(FR)Cette invention concerne une nouvelle classe de dérivés d'indolin-2-one, lesdits composés étant des inhibiteurs de protéines kinases qui sont utiles pour traiter les maladies hyperprolifératives telles que le cancer. Dans un mode de réalisation selon l'invention, le cancer est au moins un cancer choisi dans le groupe constitué par le cancer du poumon, le cancer colorectal, le cancer du foie et la leucémie aiguë myélomonocytaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)