Mobile |
Deutsch |
Español |
Français |
日本語 |
한국어 |
Português |
Русский |
中文 |
العربية |
PATENTSCOPE
Search International and National Patent Collections
Options
Query
Result
Interface
Office
Translate
«
↓
»
Query Language
All
English
Hebrew
Korean
Spanish
Vietnamese
Arabic
Estonian
Indonesian
Polish
Swedish
Chinese
French
Italian
Portuguese
Swedish
Danish
German
Japanese
Russian
Thai
Stem
Sort by:
Relevance
Pub Date Desc
Pub Date Asc
App Date Desc
App Date Asc
List Length
10
50
100
200
Result List Language
Query Language
Vietnamese
German
Italian
Arabic
Swedish
English
Hebrew
Japanese
Polish
Estonian
Spanish
Portuguese
Russian
Danish
Indonesian
Korean
French
Chinese
Swedish
Thai
Displayed Fields
Application Number
Abstract
Int. Class
Inventor Name
Publication Date
Applicant Name
Image
Chart/Graph
Table
Graph
Group by
None
IPC code
Inventors
Publication Dates
Offices of NPEs
Applicants
Filing Dates
Countries
No of Items/Group
0
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
Download Fields
NPEs
Default Search Form
Simple
Advanced Search
Field Combination
Browse by Week (PCT)
Cross Lingual Expansion
Translator
Default Tab Search Form
Front Page
Any Field
Full Text
ID/Numbers
IPC
Names
Dates
Interface Language
English
Deutsch
Français
Español
日本語
中文
한국어
Português
Русский
Skins
Default
Plain
Blue_Sky
Classic
Deep_Marine
Emerald_Town
Japan_Cherry
Ruby
Wine
Multiple Windows Interface
Tooltip Help
IPC Tooltip Help
Office:
All
All
PCT
Africa
ARIPO
Egypt
Kenya
Morocco
Tunisia
South Africa
Americas
United States of America
Canada
LATIPAT
Argentina
Brazil
Chile
Colombia
Costa Rica
Cuba
Dominican Rep.
Ecuador
El Salvador
Guatemala
Honduras
Mexico
Nicaragua
Panama
Peru
Uruguay
Asia-Europe
Australia
Bahrain
China
Denmark
Estonia
Eurasian Patent Office
European Patent Office
France
Germany
Germany(DDR data)
Israel
Japan
Jordan
Portugal
Russian Federation
Russian Federation(USSR data)
Saudi Arabia
United Arab Emirates
Spain
Republic of Korea
India
United Kingdom
Georgia
Asean
Singapore
Viet Nam
Indonesia
Cambodia
Malaysia
Brunei Darussalam
Philippines
Thailand
WIPO translate (Wipo internal translation tool)
Search
Simple
Advanced Search
Field Combination
Cross Lingual Expansion
Browse
Browse by Week (PCT)
Gazette Archive
Download National Phase Entries
Sequence listing
IPC Green Inventory
Portal to patent registers
Translate
WIPO Translate
WIPO Pearl
Options
Sort
Graph
Show Options
News
PATENTSCOPE News
Login
Login
Account Sign Up
Help
How to Search
User Guide PATENTSCOPE
User Guide: Cross Lingual Expansion
User Guide: ChemSearch
Query Syntax
Fields Definition
Country Code
Data Coverage
PCT applications
PCT national phase entry
National collections
Global Dossier public
FAQ
Feedback&Contact
INID codes
Kind codes
Tutorials
About
Overview
Terms And Conditions
Disclaimer
Home
IP Services
PATENTSCOPE
Machine translation
Wipo Translate
Arabic
German
English
Spanish
French
Japanese
Korean
Portuguese
Russian
Chinese
Google Translate
Bing/Microsoft Translate
Baidu Translate
Arabic
English
French
German
Spanish
Portuguese
Russian
Korean
Japanese
Chinese
...
Italian
Thai
Cantonese
Classical Chinese
1. (WO2013158309) NON-DISRUPTIVE GENE TARGETING
PCT Biblio. Data
Description
Claims
National Phase
Notices
Drawings
Documents
«
↓
»
Latest bibliographic data on file with the International Bureau
PermaLink
PermaLink
Bookmark
Pub. No.:
WO/2013/158309
International Application No.:
PCT/US2013/032443
Publication Date:
24.10.2013
International Filing Date:
15.03.2013
IPC:
C12N 15/85
(2006.01)
C
CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79
Vectors or expression systems specially adapted for eukaryotic hosts
85
for animal cells
Applicants:
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
[US/US]; 1705 El Camino Real Palo Alto, California 94306-1106 (US).
BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
[US/US]; 201 West 7th Street Austin, Texas 78701 (US)
Inventors:
KAY, Mark A.
; (US).
PORTEUS, Matthew
; (US).
BARKER, Jenny
; (US).
CHECKETTS, Josh
; (US).
VOIT, Richard
; (US).
BARZEL, Adi
; (US)
Agent:
ALCAMO, Elizabeth A.
; Bozicevic, Field & Francis LLP 1900 University Avenue, Suite 200 East Palo Alto, California 94303 (US)
Priority Data:
61/635,203
18.04.2012
US
61/654,645
01.06.2012
US
Title
(EN)
NON-DISRUPTIVE GENE TARGETING
(FR)
CIBLAGE GÉNIQUE NON DISRUPTIF
Abstract:
(EN)
Compositions and methods are provided for integrating one or more genes of interest into cellular DNA without substantially disrupting the expression of the gene at the locus of integration, i.e., the target locus. These compositions and methods are useful in any in vitro or in vivo application in which it is desirable to express a gene of interest in the same spatially and temporally restricted pattern as that of a gene at a target locus while maintaining the expression of the gene at the target locus, for example, to treat disease, in the production of genetically modified organisms in agriculture, in the large scale production of proteins by cells for therapeutic, diagnostic, or research purposes, in the induction of iPS cells for therapeutic, diagnostic, or research purposes, in biological research, etc. Reagents, devices and kits thereof that find use in practicing the subject methods are also provided.
(FR)
La présente invention concerne des compositions et des procédés d'intégration d'un ou de plusieurs gènes d'intérêt dans un ADN cellulaire sans sensiblement perturber l'expression du gène au niveau du locus d'intégration, en d'autres termes, du locus cible. Ces compositions et ces procédés sont utiles dans toute application in vitro ou in vivo dans laquelle l'expression d'un gène d'intérêt est souhaitable dans le même profil à restriction spatiale et temporelle que celui d'un gène au niveau d'un locus cible tout en maintenant l'expression du gène au niveau du locus cible, par exemple, pour traiter une maladie, dans la production d'organismes génétiquement modifiés en agriculture, dans la production à grande échelle de protéines par des cellules pour des fins thérapeutiques, diagnostiques, ou de recherche, dans l'induction de cellules iPs pour des fins thérapeutiques, diagnostiques, ou de recherche, pour la recherche biologique, etc. La présente invention concerne en outre des réactifs, des dispositifs et des kits les comprenant qui sont utiles pour pratiquer les procédés de l'invention.
Designated States:
AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language:
English (
EN
)
Filing Language:
English (
EN
)