WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2013158279) PROTEIN PURIFICATION METHODS TO REDUCE ACIDIC SPECIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/158279    International Application No.:    PCT/US2013/031681
Publication Date: 24.10.2013 International Filing Date: 14.03.2013
IPC:
C07K 1/16 (2006.01), C07K 1/18 (2006.01), C07K 16/24 (2006.01)
Applicants: ABBVIE INC. [US/US]; 1 North Waukegan Road North Chicago, IL 60064 (US)
Inventors: RAMASUBRAMANYAN, Natarajan; (US).
YANG, Lihua; (US).
HERIGSTAD, Matthew Omon; (US).
YANG, Hong; (US).
CHUMSAE, Christopher; (US)
Agent: LACCOTRIPE ZACHARAKIS, Maria; McCarter & English, LLP 265 Franklin Street Boston, MA 02110 (US)
Priority Data:
61/636,493 20.04.2012 US
Title (EN) PROTEIN PURIFICATION METHODS TO REDUCE ACIDIC SPECIES
(FR) PROCÉDÉS DE PURIFICATION DE PROTÉINES POUR RÉDUIRE DES ESPÈCES ACIDES
Abstract: front page image
(EN)The instant invention relates to the field of protein production and purification, and in particular to compositions and processes for controlling the amount of charge variants, aggregates, and fragments of a protein of interest, as well as host cell proteins, present in purified preparations by applying particular chromatography conditions during such protein purification.
(FR)La présente invention concerne le domaine de la production et de la purification de protéines et, en particulier, des compositions et des procédés qui permettent de réguler la quantité de variants de charge, d'agrégats et de fragments d'une protéine d'intérêt, ainsi que des protéines de cellule hôte, présentes dans des préparations purifiées, par l'application de conditions particulières de chromatographie au cours d'une telle purification de protéines.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)