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1. WO2013158230 - COMPOSITIONS AND METHODS FOR DETECTING UNSTABLE ARTERIOSCLEROTIC PLAQUES

Publication Number WO/2013/158230
Publication Date 24.10.2013
International Application No. PCT/US2013/029276
International Filing Date 06.03.2013
IPC
G01N 33/68 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
G01N 33/573 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
573for enzymes or isoenzymes
G01N 33/50 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
CPC
G01N 2800/323
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
32Cardiovascular disorders
323Arteriosclerosis, Stenosis
G01N 2800/324
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
32Cardiovascular disorders
324Coronary artery diseases, e.g. angina pectoris, myocardial infarction
G01N 2800/50
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
50Determining the risk of developing a disease
G01N 33/5308
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
5308for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
G01N 33/6893
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
6893related to diseases not provided for elsewhere
Applicants
  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US]/[US]
Inventors
  • KANE, John P.
  • CHALKLEY, Robert J.
  • MIROSHNYCHENKO, Olga
Agents
  • BORDEN, Paula A.
Priority Data
61/635,64519.04.2012US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMPOSITIONS AND METHODS FOR DETECTING UNSTABLE ARTERIOSCLEROTIC PLAQUES
(FR) COMPOSITIONS ET PROCÉDÉS DE DÉTECTION DE PLAQUES D'ATHÉROSCLÉROSE INSTABLES
Abstract
(EN)
The present disclosure provides methods of detecting an unstable arteriosclerotic plaque in an individual, involving detecting in a biological sample from the individual an enzymatic cleavage product of a protein component of an arteriosclerotic plaque. The present disclosure provides methods of assessing the risk that an individual will develop an occlusive vascular event. The present disclosure further provides kits for carrying out a subject method.
(FR)
La présente invention concerne des procédés de détection d'une plaque d'athérosclérose instable chez un individu consistant à détecter dans un échantillon biologique de l'individu un produit de coupure enzymatique d'un composant protéique d'une plaque d'athérosclérose. La présente invention concerne des procédés permettant d'évaluer le risque que présente un individu de développer un évènement vasculaire occlusif. La présente invention concerne en outre des kits permettant de mener à bien le procédé de l'invention.
Also published as
Latest bibliographic data on file with the International Bureau