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1. WO2013158047 - BIOREACTOR UNIT FOR USE IN BIOARTIFICIAL KIDNEY DEVICE

Publication Number WO/2013/158047
Publication Date 24.10.2013
International Application No. PCT/SG2013/000159
International Filing Date 22.04.2013
IPC
A61M 1/14 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14Dialysis systems; Artificial kidneys; Blood oxygenators
A61M 1/34 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
B01D 61/24 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
61Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
24Dialysis
B01D 69/08 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
69Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
08Hollow fibre membranes
CPC
A61M 1/3417
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
34Filtering material out of the blood by passing it through a membrane, i.e. haemofiltration, diafiltration
3413Diafiltration
3417using distinct filters for dialysis and ultra-filtration
A61M 1/3434
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
34Filtering material out of the blood by passing it through a membrane, i.e. haemofiltration, diafiltration
342Adding solutions to the blood, e.g. substitution solutions
3424Substitution fluid path
3431upstream the filter
3434with pre-dilution and post-dilution
A61M 1/3472
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
34Filtering material out of the blood by passing it through a membrane, i.e. haemofiltration, diafiltration
3472with treatment of the filtrate
A61M 1/3489
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
34Filtering material out of the blood by passing it through a membrane, i.e. haemofiltration, diafiltration
3472with treatment of the filtrate
3486Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
3489by biological cells
B01D 63/02
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
DSEPARATION
63Apparatus in general for separation processes using semi-permeable membranes
02Hollow fibre modules
Applicants
  • AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH [SG]/[SG]
Inventors
  • ZINK, Daniele
  • ZAY, Yar Oo
Agents
  • YUSARN AUDREY
Priority Data
61/636,19920.04.2012US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) BIOREACTOR UNIT FOR USE IN BIOARTIFICIAL KIDNEY DEVICE
(FR) UNITÉ DE BIORÉACTEUR À UTILISER DANS UN DISPOSITIF DE REIN BIOARTIFICIEL
Abstract
(EN)
There is provided a bioreactor device having cells, including human primary proximal tubule cells (HPTCs) or HPTC-like cells on the exterior surface of hollow fiber membranes included within the device. Also provided are bioartificial kidney devices incorporate the bioreactor device and methods of using such devices. FIGURE 1
(FR)
L'invention concerne un dispositif bioréacteur qui présentent des cellules, comprenant des cellules tubulaires proximales, primaires, humaines (HPTC) ou des cellules de type HPTC à la surface externe de membranes fibreuses creuses comprises à l'intérieur du dispositif. L'invention concerne également des dispositifs de rein bioartificiel incorporant le dispositif bioréacteur et des procédés d'utilisation de tels dispositifs.
Also published as
Latest bibliographic data on file with the International Bureau