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1. (WO2013157648) PHARMACEUTICAL COMPOSITION

Pub. No.:    WO/2013/157648    International Application No.:    PCT/JP2013/061686
Publication Date: Fri Oct 25 01:59:59 CEST 2013 International Filing Date: Sat Apr 20 01:59:59 CEST 2013
IPC: A61K 35/76
A61K 45/00
A61P 35/00
Applicants: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION
国立大学法人九州大学
Inventors: TANI Kenzaburo
谷 憲三朗
INOUE Hiroyuki
井上 博之
YASUNARI Keisuke
安成 啓祐
MIYAMOTO Shohei
宮本 将平
Title: PHARMACEUTICAL COMPOSITION
Abstract:
A pharmaceutical composition contains coxsackie virus type-A11 with which a cancer cell can be infected or echo virus type-4 with which a cancer cell can be infected. A capsid may be removed from the coxsackie virus type-A11 or the echo virus type-4. The pharmaceutical composition has potent cytotoxicity against a cell of a cancer selected from the group consisting of small cell lung cancer, non-small cell lung cancer, squamous cell carcinoma, malignant mesothelioma, large intestine cancer, colorectal cancer, esophageal cancer, hypopharyngeal cancer, human B lymphoma, breast cancer, cervical cancer and pancreatic cancer, which is a cancer cell of a solid cancer.