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1. (WO2013156941) DEVICE FOR OBTAINING THREE-DIMENSIONAL CELL CULTURES, METHOD FOR THE IMPLEMENTATION THEREOF, AND USE OF SUCH DEVICE

Pub. No.:    WO/2013/156941    International Application No.:    PCT/IB2013/053041
Publication Date: Fri Oct 25 01:59:59 CEST 2013 International Filing Date: Thu Apr 18 01:59:59 CEST 2013
IPC: B01L 3/00
B08B 17/00
C12M 1/34
Applicants: FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Inventors: DI FABRIZIO, Enzo
LIMONGI, Tania
GENTILE, Francesco
MAROTTA, Roberto
BENFENATI, Fabio
CESCA, Fabrizia
Title: DEVICE FOR OBTAINING THREE-DIMENSIONAL CELL CULTURES, METHOD FOR THE IMPLEMENTATION THEREOF, AND USE OF SUCH DEVICE
Abstract:
A device for obtaining three-dimensional cell cultures comprising: a substrate (1); a plurality of micro-structures (2) which protrude from the surface of the substrate (1) and are arranged on such substrate (1) according to a periodical grid so as to make the substrate (1) super hydrophobic. The device is characterised in that the micro-structures (2) have side walls at least partially nano-patterned and have projections (14) and recesses (16) alternated with a predetermined distance.