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1. WO2013156785 - DIAGNOSTIC GENE

Publication Number WO/2013/156785
Publication Date 24.10.2013
International Application No. PCT/GB2013/050988
International Filing Date 19.04.2013
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
C12Q 1/6883
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
C12Q 2600/124
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
124Animal traits, i.e. production traits, including athletic performance or the like
C12Q 2600/156
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
156Polymorphic or mutational markers
Applicants
  • ANIMAL HEALTH TRUST [GB]/[GB]
Inventors
  • MELLERSH, Cathryn Suzanne
  • FORMAN, Oliver Paul
Agents
  • GIBSON, Mark
Priority Data
1206946.420.04.2012GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DIAGNOSTIC GENE
(FR) GÈNE DIAGNOSTIQUE
Abstract
(EN)
The invention relates to the use of the β-III spectrin gene (SPTBN2) as a biomarker for the in vitro diagnosis of cerebellar cortical degeneration, to in vitro methods of assessing the cerebellar cortical degeneration status in a canine mammal and to primers and diagnostic kits for use in said method.
(FR)
L'invention concerne l'utilisation du gène de la spectrine β-III (SPTBN2) en tant que biomarqueur pour diagnostiquer in vitro la dégénérescence corticale cérébelleuse, des méthodes d'évaluation in vitro de l'état de la dégénérescence corticale cérébelleuse chez un mammifère canin, des amorces et des kits de diagnostic à utiliser dans la méthode.
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