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1. (WO2013156081) MICROFLUIDIC IMPEDANCE FLOW CYTOMETER

Pub. No.:    WO/2013/156081    International Application No.:    PCT/EP2012/057290
Publication Date: Fri Oct 25 01:59:59 CEST 2013 International Filing Date: Sat Apr 21 01:59:59 CEST 2012
IPC: G01N 15/12
Applicants: FOSS ANALYTICAL A/S
BISGAARD, Christer
LAURELL, Thomas
GRENVALL, Carl
ANTFOLK, Christian
Inventors: BISGAARD, Christer
LAURELL, Thomas
GRENVALL, Carl
ANTFOLK, Christian
Title: MICROFLUIDIC IMPEDANCE FLOW CYTOMETER
Abstract:
A microfluidic impedance flow cytometer ('MIC') device (2) comprises a substrate (4) in which is formed at least one flow channel (6) for leading through a particle (22) containing fluidic sample. The flow channel (6) is formed with a focusing zone (12) and a measurement zone (14) located downstream of the focusing zone (12) in the direction of through flow and provided with an electrode arrangement (18) for characterising particles (22) in the flowing fluidic sample by means of electrical impedance wherein an acoustophoretic particle focusing arrangement (20) is provided in acoustic coupling to the flow channel (6) in the focusing zone (12) to induce acoustic forces in fluid in the flow channel (6) so as to effect a lateral and/or vertical focusing of particles before flowing to the measurement zone (14).