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1. WO2013155592 - CRYSTAL FORMS OF GOLOTIMOD AND PROCESS FOR ITS MANUFACTURING

Publication Number WO/2013/155592
Publication Date 24.10.2013
International Application No. PCT/CA2013/000322
International Filing Date 04.04.2013
IPC
C07D 209/20 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02condensed with one carbocyclic ring
04Indoles; Hydrogenated indoles
10with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
20substituted additionally by nitrogen atoms, e.g. tryptophane
A61K 31/405 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
40having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
403condensed with carbocyclic rings, e.g. carbazole
404Indoles, e.g. pindolol
405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
C07K 5/037 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
02containing at least one abnormal peptide link
037the abnormal link being formed by the side chain of an alpha-amino acid, e.g. gamma-Glu, epsilon-Lys, glutathione
C07K 5/06 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof
04containing only normal peptide links
06Dipeptides
CPC
C07D 209/42
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
209Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
02condensed with one carbocyclic ring
04Indoles; Hydrogenated indoles
30with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
42Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07K 5/0215
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
5Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
02containing at least one abnormal peptide link
0215containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
Applicants
  • APOTEX TECHNOLOGIES INC. [CA]/[CA]
Inventors
  • TAM, Tim Fat
  • LEUNG-TOUNG, Regis
  • ZHAO, Yanqing
  • WANG, Yingsheng
Agents
  • SINDEN, William K.
Priority Data
61/625,76818.04.2012US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CRYSTAL FORMS OF GOLOTIMOD AND PROCESS FOR ITS MANUFACTURING
(FR) FORMES CRISTALLINES DE GOLOTIMOD ET PROCÉDÉ POUR SA FABRICATION
Abstract
(EN)
Crystalline forms of golotimod of the chemical structure: (I) and processes for their manufacture are provided.
(FR)
L'invention concerne des formes cristallines de golotimod de la structure chimique : (I) et des procédés pour leur fabrication.
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