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1. (WO2013155526) SORTASE- MODIFIED VHH DOMAINS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/155526    International Application No.:    PCT/US2013/036630
Publication Date: 17.10.2013 International Filing Date: 15.04.2013
IPC:
C07K 14/435 (2006.01), C07K 1/13 (2006.01), C07K 19/00 (2006.01), C07K 16/46 (2006.01), C12N 15/10 (2006.01), C12N 15/64 (2006.01), C40B 50/06 (2006.01), A61K 39/00 (2006.01), A61P 37/02 (2006.01)
Applicants: WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH [US/US]; Nine Cambridge Center Cambridge, MA 02142 (US)
Inventors: PLOEGH, Hidde; (US).
POPP, Maximilian; (US).
CRAGNOLINI, Juanjo;
Agent: TREANNIE, Lisa, M.; More, Barnes-Brown & Pendleton, P.C Citypoint 230 Third Avenue, 4th Floor Waltham, MA 02451 (US)
Priority Data:
61/624,114 13.04.2012 US
Title (EN) SORTASE- MODIFIED VHH DOMAINS AND USES THEREOF
(FR) DOMAINES VHH MODIFIÉS PAR SORTASE ET APPLICATIONS ASSOCIÉES
Abstract: front page image
(EN)In some aspects, polypeptides comprising single domain antibodies and methods of identifying single domain antibodies are provided. In some embodiments polypeptides comprising a single domain antibody and a sortase recognition sequence, are provided. In some aspects, products and methods of use in modulating the immune system, e.g., modulating an immune response, are provided.
(FR)Dans certains aspects, la présente invention concerne des polypeptides comprenant des anticorps à domaine unique et des procédés d'identification d'anticorps à domaine unique. Dans certains modes de réalisation, l'invention concerne des polypeptides comprenant un anticorps à domaine unique et une séquence de reconnaissance de sortase. Dans certains aspects, l'invention concerne des produits et des procédés d'utilisation dans la modulation du système immunitaire, par ex. la modulation d'une réponse immunitaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)