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1. (WO2013155478) METHOD FOR TREATING HYPERURICEMIA IN PATIENTS WITH GOUT USING HALOFENATE OR HALOFENIC ACID AND AN ANTI-INFLAMMATORY AGENT
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/155478 International Application No.: PCT/US2013/036474
Publication Date: 17.10.2013 International Filing Date: 12.04.2013
IPC:
A61K 31/221 (2006.01)
Applicants: SAHA, Gopal, Chandra[BD/US]; US (US)
LAVAN, Brian, Edward[GB/US]; US (US)
ROBERTS, Brian, K.[US/US]; US (US)
MCWHERTER, Charles, A.[US/US]; US (US)
CYMABAY THERAPEUTICS, INC.[US/US]; 7999 Gateway Blvd., Suite 130 Newark, California 94560, US (AllExceptUS)
Inventors: SAHA, Gopal, Chandra; US
LAVAN, Brian, Edward; US
ROBERTS, Brian, K.; US
MCWHERTER, Charles, A.; US
Agent: NGUYEN, Sam, L.; HAMILTON, DESANCTiS & CHA LLP 3239 El Camino Real, Suite 220 Palo Alto, CA 94306, US
Priority Data:
61/624,18613.04.2012US
Title (EN) METHOD FOR TREATING HYPERURICEMIA IN PATIENTS WITH GOUT USING HALOFENATE OR HALOFENIC ACID AND AN ANTI-INFLAMMATORY AGENT
(FR) MÉTHODE DE TRAITEMENT DE L'HYPERURICÉMIE, FAISANT APPEL À L'HALOFÉNATE OU À L'ACIDE HALOFÉNIQUE ET À UN AGENT ANTI-INFLAMMATOIRE, CHEZ LES PATIENTS SOUFFRANT DE GOUTTE
Abstract:
(EN) Disclosed herein are pharmaceutical compositions, methods and kits for lowering the serum uric acid level of a subject and for the treatment of a condition associated with elevated serum uric acid levels comprising administering a composition comprising a urate-lowering agent and an anti-inflammatory agent. In some aspects the urate-lowering agent is (-)- halofenate, (-)-halofenic acid, or a pharmaceutically acceptable salts thereof. In some aspects the second agent is an anti-inflammatory agent, or a pharmaceutically acceptable salt thereof.
(FR) La présente invention concerne des compositions pharmaceutiques, des méthodes et des nécessaires permettant de faire baisser le taux d'acide urique dans le sérum d'un sujet et de traiter une affection associée à des taux élevés d'acide urique dans le sérum, et ce sous l'effet de l'administration d'une composition contenant un agent permettant de faire baisser la quantité d'urates, ainsi qu'un agent anti-inflammatoire. Selon certains aspects, ledit agent capable de faire baisser la quantité d'urates est le (-)-halofénate, le (-)-acide halofénique ou des sels pharmaceutiquement acceptables de ceux-ci. Selon certains aspects, le second agent est un agent anti-inflammatoire ou un sel pharmaceutiquement acceptable de celui-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)