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1. (WO2013155456) PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/155456 International Application No.: PCT/US2013/036441
Publication Date: 17.10.2013 International Filing Date: 12.04.2013
IPC:
G01N 33/53 (2006.01) ,G01N 33/50 (2006.01) ,G01N 33/48 (2006.01)
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
Applicants: NICOLAIDES, Kypros[GB/GB]; GB
WAYNE STATE UNIVERSITY[US/US]; 656 West Kirby 4249 F.A.B. Detroit, Michigan 48202, US
Inventors: NICOLAIDES, Kypros; GB
BAHADO-SINGH, Ray; US
Agent: PETRILLO, Kathleen, M.; Senniger Powers LLP 100 North Broadway 17th Floor St. Louis, Missouri 63102, US
Priority Data:
61/623,74113.04.2012US
Title (EN) PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18
(FR) DÉPISTAGE PRÉNATAL DU SYNDROME DE DOWN ET DE LA TRISOMIE 18
Abstract:
(EN) The present invention is directed to methods for predicting a pregnant woman's risk of carrying a fetus with Down syndrome (Trisomy 21) or Trisomy 18. The methods are based on measuring one or more metabolites obtained from a pregnant woman's bodily fluid, such as blood or urine, and found to be predictive of Trisomy 21 or Trisomy 18.
(FR) La présente invention concerne des méthodes permettant de prédire le risque pour une femme enceinte que son fœtus souffre du syndrome de Down (trisomie 21) ou de trisomie 18. Lesdites méthodes sont fondées sur la mesure d'un ou plusieurs métabolites recueillis à partir d'un fluide corporel, tel que le sang ou l'urine, d'une femme enceinte, métabolites dont on s'est aperçu qu'ils permettent de prédire une trisomie 21 ou 18.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)