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1. (WO2013155404) METHODS AND COMPOSITIONS FOR PREPARING A SILK MICROSPHERE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/155404 International Application No.: PCT/US2013/036356
Publication Date: 17.10.2013 International Filing Date: 12.04.2013
IPC:
A61K 47/42 (2006.01) ,A61K 47/30 (2006.01) ,A61K 9/16 (2006.01) ,A61K 9/14 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
42
Proteins; Polypeptides; Degradation products thereof; Derivatives thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47
Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
30
Macromolecular compounds
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
16
Agglomerates; Granulates; Microbeadlets
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9
Medicinal preparations characterised by special physical form
14
Particulate form, e.g. powders
Applicants: TRUSTEES OF TUFTS COLLEGE[US/US]; Ballou Hall Medford, Massachusetts 02155, US
Inventors: KAPLAN, David L.; US
YUCEL, Tuna; US
WANG, Xiaoqin; US
LOVETT, Michael; US
Agent: JARRELL, Brenda, Herschbach; Choate, Hall & Stewart LLP Two International Place Boston, MA 02110, US
Priority Data:
61/623,97013.04.2012US
Title (EN) METHODS AND COMPOSITIONS FOR PREPARING A SILK MICROSPHERE
(FR) PROCÉDÉS ET COMPOSITIONS DESTINÉS À LA PRÉPARATION D'UNE MICROSPHÈRE EN SOIE
Abstract:
(EN) Provided herein relates to methods and compositions for preparing a silk microsphere and the resulting silk microsphere. In some embodiments, the methods and compositions described herein are all aqueous, which can be used for encapsulating an active agent in a silk microsphere, while maintaining activity of the active agent during processing. In some embodiments, the resulting silk microsphere can be used for sustained delivery of an active agent encapsulated therein.
(FR) La présente invention concerne des procédés et des compositions destinés à la préparation d'une microsphère en soie et la microsphère en soie résultante. Dans certains modes de réalisation, les procédés et compositions décrits dans la description, qui peuvent être utilisés pour l'encapsulation d'un agent actif dans une microsphère en soie, tout en conservant une activité de l'agent actif lors du traitement, sont tous aqueux. Dans certains modes de réalisation, la microsphère en soie résultante peut être utilisée pour l'administration prolongée d'un agent actif encapsulé en son sein.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)