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1. (WO2013155360) A METHOD FOR PREVENTING NEOPLASTIC TRANSFORMATION BY INHIBITION OF RETINOBLASTOMA PROTEIN INACTIVATION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2013/155360 International Application No.: PCT/US2013/036263
Publication Date: 17.10.2013 International Filing Date: 12.04.2013
IPC:
C12N 5/00 (2006.01) ,C07K 7/04 (2006.01) ,C07K 7/64 (2006.01) ,A61P 35/00 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA[US/US]; Office Of Technology Transfer 1111 Franklin Street 5th Floor Oakland, CA 94607, US
Inventors: BURKE, Jason, R.; US
RUBIN, Seth, M.; US
Agent: BELL, Adam, W.; Bell & Associates 58 West Portal Avenue # 121 San Francisco, CA 94127, US
Priority Data:
61/623,21112.04.2012US
Title (EN) A METHOD FOR PREVENTING NEOPLASTIC TRANSFORMATION BY INHIBITION OF RETINOBLASTOMA PROTEIN INACTIVATION
(FR) MÉTHODE DE PRÉVENTION DE LA TRANSFORMATION NÉOPLASIQUE PAR INHIBITION DE L'INACTIVATION DE LA PROTÉINE DU RÉTINOBLASTOME
Abstract: front page image
(EN) A method for preventing neoplastic transformation by inhibition of cell cycle progression into S phase by preventing the inactivation of Retinoblastoma protein (Rb).
(FR) La présente invention concerne une méthode de prévention de la transformation néoplasique par inhibition de l'entrée des cellules en phase S du cycle cellulaire, et ce, en empêchant l'inactivation de la protéine du rétinoblastome (Rb).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)