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1. (WO2013154712) ASYMMETRIC SYNTHESES FOR SPIRO-OXINDOLE COMPOUNDS USEFUL AS THERAPEUTIC AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2013/154712    International Application No.:    PCT/US2013/030219
Publication Date: 17.10.2013 International Filing Date: 11.03.2013
IPC:
C07D 491/20 (2006.01), A61K 31/407 (2006.01), A61P 25/00 (2006.01)
Applicants: XENON PHARMACEUTICALS INC. [CA/CA]; 3650 Gilmore Way Burnaby, British Columbia V5G 4W8 (CA)
Inventors: SUN, Shaoyi; (CA).
FU, Jianmin; (CA).
CHOWDHURY, Sultan; (CA).
HEMEON, Ivan, William; (CA).
GRIMWOOD, Michael, Edward; (CA).
MANSOUR, Tarek, Suhayl; (US)
Agent: ROTH, Carol, J.; Seed Intellectual Property Law Group PLLC Suite 5400 701 Fifth Avenue Seattle, Washington 98104-7064 (US)
Priority Data:
61/623,336 12.04.2012 US
Title (EN) ASYMMETRIC SYNTHESES FOR SPIRO-OXINDOLE COMPOUNDS USEFUL AS THERAPEUTIC AGENTS
(FR) SYNTHÈSES ASYMÉTRIQUES DE COMPOSÉS DE SPIRO-OXINDOLE UTILES COMME AGENTS THÉRAPEUTIQUES
Abstract: front page image
(EN)This invention is directed to asymmetric syntheses of certain spiro-oxindole derivatives, which are useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.
(FR)La présente invention concerne des synthèses asymétriques de certains dérivés de spiro-oxindole, ces dérivés étant utiles pour traiter et/ou prévenir des maladies ou affections médiées par les canaux sodiques, telles que la douleur.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)