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1. (WO2013154128) NOVEL ARTERIOSCLEROSIS TREATMENT DRUG COMPOSITION AND METHOD FOR SCREENING ARTERIOSCLEROSIS TREATMENT DRUGS

Pub. No.:    WO/2013/154128    International Application No.:    PCT/JP2013/060798
Publication Date: Fri Oct 18 01:59:59 CEST 2013 International Filing Date: Thu Apr 11 01:59:59 CEST 2013
IPC: A61K 45/00
A61K 31/7088
A61K 31/7105
A61K 35/76
A61K 48/00
A61P 3/06
A61P 9/10
A61P 25/28
C12N 15/113
C12Q 1/02
C12Q 1/68
G01N 33/15
G01N 33/50
Applicants: SHIONOGI & CO., LTD.
塩野義製薬株式会社
Inventors: YAMAGUCHI, Yoko
山口 陽子
ROKUSHIMA, Masatomo
六嶋 正知
YAMAMOTO, Shigenori
山本 薫紀
ITOH, Takeshi
伊藤 剛
MAEKAWA, Kazuhiko
前川 和彦
Title: NOVEL ARTERIOSCLEROSIS TREATMENT DRUG COMPOSITION AND METHOD FOR SCREENING ARTERIOSCLEROSIS TREATMENT DRUGS
Abstract:
The present invention pertains to: the use as the target of treatment for dyslipidemia, hyperlipidemia, arteriosclerosis, or Alzheimer's disease of a gene coding for the human CTNNB1, human NFE2L2, human TXN, human CUL1, human RAE1, human TNFRSF10C, human BCLAF1, human TNIP1, human STK38, human ZC3H13, human C14orf122, human C4orf18, human ARS2, human C4orf20, human RC74, human EP400, human RUFY1, human EPPK1, human SLA2, human FTMT, human GPR139, human OR10AG1, human C1QTNF9, human UBE2NL, human FLJ16734 or human FLJ38596 proteins; a treatment agent for dyslipidemia, hyperlipidemia, arteriosclerosis, or Alzheimer's disease targeting the genes; and a method for screening treatment agents for dyslipidemia, hyperlipidemia, arteriosclerosis, or Alzheimer's disease targeting the genes.