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Pub. No.: WO/2013/153407 International Application No.: PCT/GB2013/050959
Publication Date: 17.10.2013 International Filing Date: 15.04.2013
C07F 15/00 (2006.01) ,B01J 23/46 (2006.01) ,C07B 31/00 (2006.01)
Applicants: THE UNIVERSITY OF LIVERPOOL[GB/GB]; Foundation Building 765 Brownlow Hill Liverpool L69 7ZX, GB
Inventors: TALWAR, Dinesh; GB
TANG, Weijun; GB
WANG, Chao; GB
XIAO, Jianliang; GB
Agent: HARRISON GODDARD FOOTE; 4th Floor, Merchant Exchange 17-1S Whitworth Street West Manchester M1 5WG, GB
Priority Data:
Abstract: front page image
(EN) The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formulas: where ring B is either itself polycyclic, or ring B together with R is polycyclic. The catalysts of the invention are particularly effective in reductive amination procedures 10 which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions.
(FR) Cette invention concerne un composé de type catalyseur à base d'iridium pour hydrogéner des fragments réductibles, notamment des imines et des iminiums, les composés de type catalyseur selon l'invention étant définis par les formules où Cycle B est soit lui-même polycyclique, soit Cycle B avec R est polycyclique. Les catalyseurs selon l'invention sont particulièrement efficaces dans les procédés d'amination réductrice qui impliquent la génération in situ de l'imine ou de l'iminium dans des conditions d'hydrogénation réductrices.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)